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Novel Celecoxib Derivative, RF26, Blocks Colon Cancer Cell Growth by Inhibiting PDE5, Activating cGMP/PKG Signaling, and Suppressing β-catenin-dependent Transcription.
Sigler S, Abdel-Halim M, Fathalla RK, Da Silva LM, Keeton AB, Maxuitenko YY, Berry K, Zhou G, Engel M, Abadi AH, Piazza GA. Sigler S, et al. Among authors: maxuitenko yy. Anticancer Agents Med Chem. 2024 Sep 2. doi: 10.2174/0118715206318802240821114353. Online ahead of print. Anticancer Agents Med Chem. 2024. PMID: 39225209
Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats.
Tinsley HN, Mathew B, Chen X, Maxuitenko YY, Li N, Lowe WM, Whitt JD, Zhang W, Gary BD, Keeton AB, Grizzle WE, Grubbs CJ, Reynolds RC, Piazza GA. Tinsley HN, et al. Among authors: maxuitenko yy. Cancers (Basel). 2023 Jan 20;15(3):646. doi: 10.3390/cancers15030646. Cancers (Basel). 2023. PMID: 36765604 Free PMC article.
Assessment of KRASG12C inhibitors for colorectal cancer.
Piazza GA, Chandrasekaran P, Maxuitenko YY, Budhwani KI. Piazza GA, et al. Among authors: maxuitenko yy. Front Oncol. 2024 Jun 24;14:1412435. doi: 10.3389/fonc.2024.1412435. eCollection 2024. Front Oncol. 2024. PMID: 38978742 Free PMC article. Review.
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer.
Foote JB, Mattox TE, Keeton AB, Chen X, Smith F, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Maxuitenko Y, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponenko V, Abdelkarim H, Boyd MR, Gorman GS, Manne U, Bae S, El-Rayes BF, Piazza GA. Foote JB, et al. bioRxiv [Preprint]. 2024 Jun 5:2023.05.17.541233. doi: 10.1101/2023.05.17.541233. bioRxiv. 2024. PMID: 38328254 Free PMC article. Preprint.
Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS.
Ward AB, Keeton AB, Chen X, Mattox TE, Coley AB, Maxuitenko YY, Buchsbaum DJ, Randall TD, Zhou G, Piazza GA. Ward AB, et al. Among authors: maxuitenko yy. MedComm (2020). 2020 Sep;1(2):121-128. doi: 10.1002/mco2.10. Epub 2020 Jun 25. MedComm (2020). 2020. PMID: 33073260 Free PMC article.
Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy.
Emmanouilidi A, Casari I, Gokcen Akkaya B, Maffucci T, Furic L, Guffanti F, Broggini M, Chen X, Maxuitenko YY, Keeton AB, Piazza GA, Linton KJ, Falasca M. Emmanouilidi A, et al. Among authors: maxuitenko yy. Cancers (Basel). 2020 Jul 23;12(8):2022. doi: 10.3390/cancers12082022. Cancers (Basel). 2020. PMID: 32718079 Free PMC article.
Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition.
Tinsley HN, Gary BD, Thaiparambil J, Li N, Lu W, Li Y, Maxuitenko YY, Keeton AB, Piazza GA. Tinsley HN, et al. Among authors: maxuitenko yy. Cancer Prev Res (Phila). 2010 Oct;3(10):1303-13. doi: 10.1158/1940-6207.CAPR-10-0030. Epub 2010 Sep 28. Cancer Prev Res (Phila). 2010. PMID: 20876730 Free PMC article.
17 results