He XH - Search Results

1

Baicalin inhibits PANoptosis by blocking mitochondrial Z-DNA formation and ZBP1-PANoptosome assembly in macrophages.

You YP, Yan L, Ke HY, Li YP, Shi ZJ, Zhou ZY, Yang HY, Yuan T, Gan YQ, Lu N, Xu LH, Hu B, Ou-Yang DY, Zha QB, He XH. You YP, et al. Among authors: he xh. Acta Pharmacol Sin. 2024 Sep 2. doi: 10.1038/s41401-024-01376-8. Online ahead of print. Acta Pharmacol Sin. 2024. PMID: 39223367

2

Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways.

Zhong CS, Zeng B, Qiu JH, Xu LH, Zhong MY, Huang YT, Xu R, Liu SY, Zha QB, Hu B, Ou-Yang DY, He XH. Zhong CS, et al. Among authors: he xh. Acta Pharmacol Sin. 2022 May;43(5):1324-1336. doi: 10.1038/s41401-021-00749-7. Epub 2021 Aug 10. Acta Pharmacol Sin. 2022. PMID: 34376811 Free PMC article.

3

Theaflavin mitigates acute gouty peritonitis and septic organ injury in mice by suppressing NLRP3 inflammasome assembly.

Chen SY, Li YP, You YP, Zhang HR, Shi ZJ, Liang QQ, Yuan T, Xu R, Xu LH, Zha QB, Ou-Yang DY, He XH. Chen SY, et al. Among authors: he xh. Acta Pharmacol Sin. 2023 Oct;44(10):2019-2036. doi: 10.1038/s41401-023-01105-7. Epub 2023 May 23. Acta Pharmacol Sin. 2023. PMID: 37221235 Free PMC article.

4

Triptolide induces PANoptosis in macrophages and causes organ injury in mice.

Zhang HR, Li YP, Shi ZJ, Liang QQ, Chen SY, You YP, Yuan T, Xu R, Xu LH, Ouyang DY, Zha QB, He XH. Zhang HR, et al. Among authors: he xh. Apoptosis. 2023 Dec;28(11-12):1646-1665. doi: 10.1007/s10495-023-01886-6. Epub 2023 Sep 13. Apoptosis. 2023. PMID: 37702860

5

Blocking reverse electron transfer-mediated mitochondrial DNA oxidation rescues cells from PANoptosis.

Shi FL, Li Q, Xu R, Yuan LS, Chen Y, Shi ZJ, Li YP, Zhou ZY, Xu LH, Zha QB, Hu B, He XH, Ou-Yang DY. Shi FL, et al. Among authors: he xh. Acta Pharmacol Sin. 2024 Mar;45(3):594-608. doi: 10.1038/s41401-023-01182-8. Epub 2023 Nov 14. Acta Pharmacol Sin. 2024. PMID: 37964019

6

Inflammatory cell death PANoptosis is induced by the anti-cancer curaxin CBL0137 via eliciting the assembly of ZBP1-associated PANoptosome.

Li YP, Zhou ZY, Yan L, You YP, Ke HY, Yuan T, Yang HY, Xu R, Xu LH, Ouyang DY, Zha QB, He XH. Li YP, et al. Among authors: he xh. Inflamm Res. 2024 Apr;73(4):597-617. doi: 10.1007/s00011-024-01858-9. Epub 2024 Feb 14. Inflamm Res. 2024. PMID: 38353723

7

Scutellarin inhibits inflammatory PANoptosis by diminishing mitochondrial ROS generation and blocking PANoptosome formation.

Yuan T, Yang HY, Li YP, Shi ZJ, Zhou ZY, You YP, Ke HY, Yan L, Xu LH, Ouyang DY, He XH, Zha QB. Yuan T, et al. Among authors: he xh. Int Immunopharmacol. 2024 Sep 30;139:112710. doi: 10.1016/j.intimp.2024.112710. Epub 2024 Jul 18. Int Immunopharmacol. 2024. PMID: 39029229

8

Identification of a novel splice variant of human PD-L1 mRNA encoding an isoform-lacking Igv-like domain.

He XH, Xu LH, Liu Y. He XH, et al. Acta Pharmacol Sin. 2005 Apr;26(4):462-8. doi: 10.1111/j.1745-7254.2005.00086.x. Acta Pharmacol Sin. 2005. PMID: 15780196

9

Enhancement of binding activity of soluble human CD40 to CD40 ligand through incorporation of an isoleucine zipper motif.

He XH, Xu LH, Liu Y. He XH, et al. Acta Pharmacol Sin. 2006 Mar;27(3):333-8. doi: 10.1111/j.1745-7254.2006.00285.x. Acta Pharmacol Sin. 2006. PMID: 16490170

10

The immunosuppressive effect of gossypol in mice is mediated by inhibition of lymphocyte proliferation and by induction of cell apoptosis.

Xu WB, Xu LH, Lu HS, Ou-Yang DY, Shi HJ, Di JF, He XH. Xu WB, et al. Among authors: he xh. Acta Pharmacol Sin. 2009 May;30(5):597-604. doi: 10.1038/aps.2009.35. Epub 2009 Apr 13. Acta Pharmacol Sin. 2009. PMID: 19363517 Free PMC article.

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