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Page 1
RAS-ON inhibition overcomes clinical resistance to KRAS G12C-OFF covalent blockade.
Nokin MJ, Mira A, Patrucco E, Ricciuti B, Cousin S, Soubeyran I, San José S, Peirone S, Caizzi L, Vietti Michelina S, Bourdon A, Wang X, Alvarez-Villanueva D, Martínez-Iniesta M, Vidal A, Rodrigues T, García-Macías C, Awad MM, Nadal E, Villanueva A, Italiano A, Cereda M, Santamaría D, Ambrogio C. Nokin MJ, et al. Among authors: bourdon a. Nat Commun. 2024 Aug 30;15(1):7554. doi: 10.1038/s41467-024-51828-2. Nat Commun. 2024. PMID: 39215000 Free PMC article.
CHK1 inhibition in soft-tissue sarcomas: biological and clinical implications.
Laroche-Clary A, Lucchesi C, Rey C, Verbeke S, Bourdon A, Chaire V, Algéo MP, Cousin S, Toulmonde M, Vélasco V, Shutzman J, Savina A, Le Loarer F, Italiano A. Laroche-Clary A, et al. Among authors: bourdon a. Ann Oncol. 2018 Apr 1;29(4):1023-1029. doi: 10.1093/annonc/mdy039. Ann Oncol. 2018. PMID: 29409053 Free article. Clinical Trial.
Expression of Concern to: Identifying and targeting cancer stem cells in leiomyosarcoma: prognostic impact and role to overcome secondary resistance to PI3K/mTOR inhibition.
Fourneaux B, Bourdon A, Dadone B, Lucchesi C, Daigle SR, Richard E, Laroche-Clary A, Le Loarer F, Italiano A. Fourneaux B, et al. Among authors: bourdon a. J Hematol Oncol. 2019 Nov 22;12(1):116. doi: 10.1186/s13045-019-0825-3. J Hematol Oncol. 2019. PMID: 31753040 Free PMC article.
Genome-wide CRISPR/Cas9 library screening identified ATM signaling network genes as critical drivers for resistance to ATR inhibition in soft-tissue sarcomas: synthetic lethality and therapeutic implications.
Spalato-Ceruso M, Laroche-Clary A, Perret R, Valverde Y, Chaire V, Derieppe MA, Velasco V, Bourdon A, Italiano A. Spalato-Ceruso M, et al. Among authors: bourdon a. Exp Hematol Oncol. 2023 May 31;12(1):51. doi: 10.1186/s40164-023-00416-z. Exp Hematol Oncol. 2023. PMID: 37259134 Free PMC article.
Antitumor Effects of PRMT5 Inhibition in Sarcomas.
Verbeke S, Bourdon A, Guegan JP, Leroy L, Chaire V, Richard E, Bessede A, Italiano A. Verbeke S, et al. Among authors: bourdon a. Cancer Res Commun. 2023 Nov 2;3(11):2211-2220. doi: 10.1158/2767-9764.CRC-23-0239. Cancer Res Commun. 2023. PMID: 37861293 Free PMC article.
Molecular profiling of advanced soft-tissue sarcomas: the MULTISARC randomized trial.
Italiano A, Dinart D, Soubeyran I, Bellera C, Espérou H, Delmas C, Mercier N, Albert S, Poignie L, Boland A, Bourdon A, Geneste D, Cavaille Q, Laizet Y, Khalifa E, Auzanneau C, Squiban B, Truffaux N, Olaso R, Gerber Z, Wallet C, Bénard A, Blay JY, Laurent-Puig P, Deleuze JF, Lucchesi C, Mathoulin-Pelissier S; MULTISARC study group. Italiano A, et al. Among authors: bourdon a. BMC Cancer. 2021 Nov 5;21(1):1180. doi: 10.1186/s12885-021-08878-2. BMC Cancer. 2021. PMID: 34740331 Free PMC article.
Integration of pre-treatment computational radiomics, deep radiomics, and transcriptomics enhances soft-tissue sarcoma patient prognosis.
Crombé A, Lucchesi C, Bertolo F, Kind M, Spalato-Ceruso M, Toulmonde M, Chaire V, Michot A, Coindre JM, Perret R, Le Loarer F, Bourdon A, Italiano A. Crombé A, et al. Among authors: bourdon a. NPJ Precis Oncol. 2024 Jun 7;8(1):129. doi: 10.1038/s41698-024-00616-8. NPJ Precis Oncol. 2024. PMID: 38849448 Free PMC article.
Feasibility of high-throughput sequencing in clinical routine cancer care: lessons from the cancer pilot project of the France Genomic Medicine 2025 plan.
FGM 2025 Workflow Study Group (Alliance nationale des Sciences de la Vie et de la Santé); Auzanneau C, Bacq D, Bellera C, Blons H, Boland A, Boucheix M, Bourdon A, Chollet E, Chomienne C, Deleuze JF, Delmas C, Dinart D, Espérou H, Geillon F, Geneste D, Italiano A, Jean D, Khalifa E, Laizet Y, Laurent-Puig P, Lethimonnier F, Lévy-Marchal C, Lucchesi C, Malle C, Mancini P, Mathoulin-Pélissier S, Meyer V, Marie-Ange P, Perkins G, Sellan-Albert S, Soubeyran I, Wallet C. FGM 2025 Workflow Study Group (Alliance nationale des Sciences de la Vie et de la Santé), et al. Among authors: bourdon a. ESMO Open. 2020 Jul;5(4):e000744. doi: 10.1136/esmoopen-2020-000744. ESMO Open. 2020. PMID: 32713836 Free PMC article.
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