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Pharmacological inhibition of N-Acylethanolamine acid amidase (NAAA) mitigates intestinal fibrosis through modulation of macrophage activity.
Nanì MF, Pagano E, De Cicco P, Lucariello G, Cattaneo F, Tropeano FP, Cicia D, Amico R, Raucci F, Ercolano G, Maione F, Rinaldi MM, Esposito F, Ammendola R, Luglio G, Capasso R, Makriyannis A, Petrosino S, Borrelli F, Romano B, Izzo AA. Nanì MF, et al. Among authors: de cicco p. J Crohns Colitis. 2024 Aug 30:jjae132. doi: 10.1093/ecco-jcc/jjae132. Online ahead of print. J Crohns Colitis. 2024. PMID: 39211986
TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β-catenin signalling.
Pagano E, Romano B, Cicia D, Iannotti FA, Venneri T, Lucariello G, Nanì MF, Cattaneo F, De Cicco P, D'Armiento M, De Luca M, Lionetti R, Lama S, Stiuso P, Zoppoli P, Falco G, Marchianò S, Fiorucci S, Capasso R, Di Marzo V, Borrelli F, Izzo AA. Pagano E, et al. Among authors: de cicco p. Br J Pharmacol. 2023 Jan;180(2):235-251. doi: 10.1111/bph.15960. Epub 2022 Oct 17. Br J Pharmacol. 2023. PMID: 36168728 Free PMC article.
Anti-metastatic Properties of Naproxen-HBTA in a Murine Model of Cutaneous Melanoma.
Ercolano G, De Cicco P, Frecentese F, Saccone I, Corvino A, Giordano F, Magli E, Fiorino F, Severino B, Calderone V, Citi V, Cirino G, Ianaro A. Ercolano G, et al. Among authors: de cicco p. Front Pharmacol. 2019 Feb 8;10:66. doi: 10.3389/fphar.2019.00066. eCollection 2019. Front Pharmacol. 2019. PMID: 30800067 Free PMC article.
32 results