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Preclinical characterization of [18F]D2-LW223: an improved metabolically stable PET tracer for imaging the translocator protein 18 kDa (TSPO) in neuroinflammatory rodent models and non-human primates.
Liao K, Chen JH, Ma J, Dong CC, Bi CY, Gao YB, Jiang YF, Wang T, Wei HY, Hou L, Hu JQ, Wei JJ, Zeng CY, Li YL, Yan S, Xu H, Liang SH, Wang L. Liao K, et al. Among authors: li yl. Acta Pharmacol Sin. 2024 Aug 29. doi: 10.1038/s41401-024-01375-9. Online ahead of print. Acta Pharmacol Sin. 2024. PMID: 39210042
Assessment of cholesterol homeostasis in the living human brain.
Haider A, Zhao C, Wang L, Xiao Z, Rong J, Xia X, Chen Z, Pfister SK, Mast N, Yutuc E, Chen J, Li Y, Shao T, Warnock GI, Dawoud A, Connors TR, Oakley DH, Wei H, Wang J, Zheng Z, Xu H, Davenport AT, Daunais JB, Van RS, Shao Y, Wang Y, Zhang MR, Gebhard C, Pikuleva I, Levey AI, Griffiths WJ, Liang SH. Haider A, et al. Sci Transl Med. 2022 Oct 5;14(665):eadc9967. doi: 10.1126/scitranslmed.adc9967. Epub 2022 Oct 5. Sci Transl Med. 2022. PMID: 36197966 Free PMC article.
Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA receptors.
Korff M, Chaudhary A, Li Y, Zhou X, Zhao C, Rong J, Chen J, Xiao Z, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Wang L, Abate C, Ahmed H, Crowe R, Liang SH, Ametamey SM, Wünsch B, Haider A. Korff M, et al. Res Sq [Preprint]. 2023 Jan 27:rs.3.rs-2516002. doi: 10.21203/rs.3.rs-2516002/v1. Res Sq. 2023. Update in: J Med Chem. 2023 Dec 14;66(23):16018-16031. doi: 10.1021/acs.jmedchem.3c01441. PMID: 36747738 Free PMC article. Updated. Preprint.
Structure-activity relationship of pyrazol-4-yl-pyridine derivatives and identification of a radiofluorinated probe for imaging the muscarinic acetylcholine receptor M4.
Haider A, Deng X, Mastromihalis O, Pfister SK, Jeppesen TE, Xiao Z, Pham V, Sun S, Rong J, Zhao C, Chen J, Li Y, Connors TR, Davenport AT, Daunais JB, Hosseini V, Ran W, Christopoulos A, Wang L, Valant C, Liang SH. Haider A, et al. Acta Pharm Sin B. 2023 Jan;13(1):213-226. doi: 10.1016/j.apsb.2022.07.008. Epub 2022 Jul 21. Acta Pharm Sin B. 2023. PMID: 36815036 Free PMC article.
Imaging Cholinergic Receptors in the Brain by Positron Emission Tomography.
Zhang JJ, Fu H, Lin R, Zhou J, Haider A, Fang W, Elghazawy NH, Rong J, Chen J, Li Y, Ran C, Collier TL, Chen Z, Liang SH. Zhang JJ, et al. J Med Chem. 2023 Aug 24;66(16):10889-10916. doi: 10.1021/acs.jmedchem.3c00573. Epub 2023 Aug 15. J Med Chem. 2023. PMID: 37583063 Free PMC article. Review.
Evaluation of [18F]RoSMA-18-d6 as a CB2 PET Radioligand in Nonhuman Primates.
Haider A, Wang L, Gobbi L, Li Y, Chaudhary A, Zhou X, Chen J, Zhao C, Rong J, Xiao Z, Hou L, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Ahmed H, Crowe R, Honer M, Rominger A, Grether U, Liang SH, Ametamey SM. Haider A, et al. ACS Chem Neurosci. 2023 Oct 18;14(20):3752-3760. doi: 10.1021/acschemneuro.3c00222. Epub 2023 Oct 3. ACS Chem Neurosci. 2023. PMID: 37788055
2,831 results