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Large-scale copy number alterations are enriched for synthetic viability in BRCA1/BRCA2 tumors.
Zhu Y, Pei X, Novaj A, Setton J, Bronder D, Derakhshan F, Selenica P, McDermott N, Orman M, Plum S, Subramanyan S, Braverman SH, McMillan B, Sinha S, Ma J, Gazzo A, Khan A, Bakhoum S, Powell SN, Reis-Filho JS, Riaz N. Zhu Y, et al. Among authors: mcdermott n. Genome Med. 2024 Aug 28;16(1):108. doi: 10.1186/s13073-024-01371-y. Genome Med. 2024. PMID: 39198848 Free PMC article.
Increased Synthetic Cytotoxicity of Combinatorial Chemoradiation Therapy in Homologous Recombination Deficient Tumors.
Ma J, Shah R, Bell AC, McDermott N, Pei X, Selenica P, Haseltine J, Delsite R, Khan AJ, Lok BH, Ellis MJ, Aft RF, Setton J, Reis-Filho JS, Riaz N, Powell SN. Ma J, et al. Among authors: mcdermott n. Int J Radiat Oncol Biol Phys. 2024 Jul 10:S0360-3016(24)02946-8. doi: 10.1016/j.ijrobp.2024.06.037. Online ahead of print. Int J Radiat Oncol Biol Phys. 2024. PMID: 38997095
Genotype-Directed Synthetic Cytotoxicity of ATR Inhibition with Radiotherapy.
Ng V, Sinha S, Novaj A, Ma J, McDermott N, Pei X, Longhini ALF, Grimsley H, Gardner R, Rosen E, Powell SN, Pareja F, Mandelker D, Khan A, Setton J, Roulston A, Morris S, Koehler M, Lee N, Reis-Filho J, Riaz N. Ng V, et al. Among authors: mcdermott n. Clin Cancer Res. 2024 Aug 7:OF1-OF14. doi: 10.1158/1078-0432.CCR-24-0154. Online ahead of print. Clin Cancer Res. 2024. PMID: 39109923
RAD52 resolves transcription-replication conflicts to mitigate R-loop induced genome instability.
Jalan M, Sharma A, Pei X, Weinhold N, Buechelmaier ES, Zhu Y, Ahmed-Seghir S, Ratnakumar A, Di Bona M, McDermott N, Gomez-Aguilar J, Anderson KS, Ng CKY, Selenica P, Bakhoum SF, Reis-Filho JS, Riaz N, Powell SN. Jalan M, et al. Among authors: mcdermott n. Nat Commun. 2024 Sep 5;15(1):7776. doi: 10.1038/s41467-024-51784-x. Nat Commun. 2024. PMID: 39237529 Free PMC article.
YB-1: The key to personalised prostate cancer management?
Bates M, Boland A, McDermott N, Marignol L. Bates M, et al. Among authors: mcdermott n. Cancer Lett. 2020 Oct 10;490:66-75. doi: 10.1016/j.canlet.2020.07.006. Epub 2020 Jul 16. Cancer Lett. 2020. PMID: 32681926 Free article. Review.
63 results