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Page 1
Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb/IIIa dependent platelet activation.
Stegner D, Göb V, Krenzlin V, Beck S, Hemmen K, Schuhmann MK, Schörg BF, Hackenbroch C, May F, Burkard P, Pinnecker J, Zernecke A, Rosenberger P, Greinacher A, Pichler BJ, Heinze KG, Stoll G, Nieswandt B. Stegner D, et al. Among authors: schuhmann mk. Nat Cardiovasc Res. 2022 Feb;1(2):132-141. doi: 10.1038/s44161-021-00017-1. Epub 2022 Feb 10. Nat Cardiovasc Res. 2022. PMID: 39195988 Free PMC article.
Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature.
Kleinschnitz C, Kraft P, Dreykluft A, Hagedorn I, Göbel K, Schuhmann MK, Langhauser F, Helluy X, Schwarz T, Bittner S, Mayer CT, Brede M, Varallyay C, Pham M, Bendszus M, Jakob P, Magnus T, Meuth SG, Iwakura Y, Zernecke A, Sparwasser T, Nieswandt B, Stoll G, Wiendl H. Kleinschnitz C, et al. Among authors: schuhmann mk. Blood. 2013 Jan 24;121(4):679-91. doi: 10.1182/blood-2012-04-426734. Epub 2012 Nov 15. Blood. 2013. PMID: 23160472 Free PMC article.
Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.
Bittner S, Ruck T, Schuhmann MK, Herrmann AM, Moha ou Maati H, Bobak N, Göbel K, Langhauser F, Stegner D, Ehling P, Borsotto M, Pape HC, Nieswandt B, Kleinschnitz C, Heurteaux C, Galla HJ, Budde T, Wiendl H, Meuth SG. Bittner S, et al. Among authors: schuhmann mk. Nat Med. 2013 Sep;19(9):1161-5. doi: 10.1038/nm.3303. Epub 2013 Aug 11. Nat Med. 2013. PMID: 23933981
CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.
Schuhmann MK, Kraft P, Stoll G, Lorenz K, Meuth SG, Wiendl H, Nieswandt B, Sparwasser T, Beyersdorf N, Kerkau T, Kleinschnitz C. Schuhmann MK, et al. J Cereb Blood Flow Metab. 2015 Jan;35(1):6-10. doi: 10.1038/jcbfm.2014.175. Epub 2014 Oct 15. J Cereb Blood Flow Metab. 2015. PMID: 25315859 Free PMC article.
Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation.
Göb E, Reymann S, Langhauser F, Schuhmann MK, Kraft P, Thielmann I, Göbel K, Brede M, Homola G, Solymosi L, Stoll G, Geis C, Meuth SG, Nieswandt B, Kleinschnitz C. Göb E, et al. Among authors: schuhmann mk. Ann Neurol. 2015 May;77(5):784-803. doi: 10.1002/ana.24380. Epub 2015 Mar 13. Ann Neurol. 2015. PMID: 25628066
98 results