Fabian E - Search Results

1

Effect of vehicle on the in vitro penetration and metabolism of genistein and daidzein in ex vivo skin explants and the Phenion full-thickness skin model.

Géniès C, Jeanjean C, Najjar A, Schepky A, Lange D, Kühnl J, Fabian E, Zifle A, Duplan H, Hewitt NJ, Jacques C. Géniès C, et al. Among authors: fabian e. J Appl Toxicol. 2024 Aug 27. doi: 10.1002/jat.4693. Online ahead of print. J Appl Toxicol. 2024. PMID: 39191459

2

Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol.

Hewitt NJ, Grégoire S, Cubberley R, Duplan H, Eilstein J, Ellison C, Lester C, Fabian E, Fernandez J, Géniès C, Jacques-Jamin C, Klaric M, Rothe H, Sorrell I, Lange D, Schepky A. Hewitt NJ, et al. Among authors: fabian e. J Appl Toxicol. 2020 Mar;40(3):403-415. doi: 10.1002/jat.3913. Epub 2019 Dec 22. J Appl Toxicol. 2020. PMID: 31867769 Free PMC article.

3

Response to "OECD 428 in vitro dermal absorption mass balance performance based on our in-house database of pesticide studies".

Kluxen FM, Grégoire S, Schepky A, Hewitt NJ, Klaric M, Domoradzki JY, Felkers E, Fisher P, McEuen SF, Parr-Dobrzanski R, Fabian E, Wiemann C. Kluxen FM, et al. Among authors: fabian e. Regul Toxicol Pharmacol. 2020 Aug;115:104707. doi: 10.1016/j.yrtph.2020.104707. Epub 2020 Jun 6. Regul Toxicol Pharmacol. 2020. PMID: 32512117 No abstract available.

4

Metabolism and plasma protein binding of 16 straight- and branched-chain parabens in in vitro liver and skin models.

Lester C, Hewitt NJ, Müller-Vieira U, Mayer M, Ellison C, Duplan H, Genies C, Jacques-Jamin C, Fabian E, Sorrell I, Lange D, Schepky A, Grégoire S. Lester C, et al. Among authors: fabian e. Toxicol In Vitro. 2021 Apr;72:105051. doi: 10.1016/j.tiv.2020.105051. Epub 2020 Nov 11. Toxicol In Vitro. 2021. PMID: 33188879 Free article.

5

Next-generation risk assessment read-across case study: application of a 10-step framework to derive a safe concentration of daidzein in a body lotion.

Najjar A, Kühnl J, Lange D, Géniès C, Jacques C, Fabian E, Zifle A, Hewitt NJ, Schepky A. Najjar A, et al. Among authors: fabian e. Front Pharmacol. 2024 Jun 19;15:1421601. doi: 10.3389/fphar.2024.1421601. eCollection 2024. Front Pharmacol. 2024. PMID: 38962304 Free PMC article.

6

Characterization of the in vitro penetration and first-pass metabolism of genistein and daidzein using human and pig skin explants and Phenion full-thickness skin models.

Géniès C, Jeanjean C, Najjar A, Schepky A, Lange D, Kühnl J, Fabian E, Zifle A, Duplan H, Hewitt NJ, Jacques C. Géniès C, et al. Among authors: fabian e. J Appl Toxicol. 2024 Aug 27. doi: 10.1002/jat.4689. Online ahead of print. J Appl Toxicol. 2024. PMID: 39191458

7

Development and validation of PBPK models for genistein and daidzein for use in a next-generation risk assessment.

Najjar A, Lange D, Géniès C, Kuehnl J, Zifle A, Jacques C, Fabian E, Hewitt N, Schepky A. Najjar A, et al. Among authors: fabian e. Front Pharmacol. 2024 Oct 3;15:1421650. doi: 10.3389/fphar.2024.1421650. eCollection 2024. Front Pharmacol. 2024. PMID: 39421667 Free PMC article.

8

Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).

Götz C, Pfeiffer R, Tigges J, Blatz V, Jäckh C, Freytag EM, Fabian E, Landsiedel R, Merk HF, Krutmann J, Edwards RJ, Pease C, Goebel C, Hewitt N, Fritsche E. Götz C, et al. Among authors: fabian e. Exp Dermatol. 2012 May;21(5):358-63. doi: 10.1111/j.1600-0625.2012.01486.x. Exp Dermatol. 2012. PMID: 22509833

9

Dermal uptake and excretion of 14C-toluene diisocyante (TDI) and 14C-methylene diphenyl diisocyanate (MDI) in male rats. Clinical signs and histopathology following dermal exposure of male rats to TDI.

Hoffmann HD, Leibold E, Ehnes C, Fabian E, Landsiedel R, Gamer A, Poole A. Hoffmann HD, et al. Among authors: fabian e. Toxicol Lett. 2010 Dec 15;199(3):364-71. doi: 10.1016/j.toxlet.2010.09.021. Epub 2010 Oct 7. Toxicol Lett. 2010. PMID: 20933064

10

In vitro dermal absorption of metiram using human skin preparations.

Fabian E, Rosenbaum C, Kratzer B, Melching-Kollmuss S. Fabian E, et al. Toxicol Lett. 2020 May 4;330:65-70. doi: 10.1016/j.toxlet.2020.03.019. Online ahead of print. Toxicol Lett. 2020. PMID: 32380121

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