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CDCA7 is an evolutionarily conserved hemimethylated DNA sensor in eukaryotes.
Wassing IE, Nishiyama A, Shikimachi R, Jia Q, Kikuchi A, Hiruta M, Sugimura K, Hong X, Chiba Y, Peng J, Jenness C, Nakanishi M, Zhao L, Arita K, Funabiki H. Wassing IE, et al. Among authors: nishiyama a. Sci Adv. 2024 Aug 23;10(34):eadp5753. doi: 10.1126/sciadv.adp5753. Epub 2024 Aug 23. Sci Adv. 2024. PMID: 39178260 Free PMC article.
Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance.
Ishiyama S, Nishiyama A, Saeki Y, Moritsugu K, Morimoto D, Yamaguchi L, Arai N, Matsumura R, Kawakami T, Mishima Y, Hojo H, Shimamura S, Ishikawa F, Tajima S, Tanaka K, Ariyoshi M, Shirakawa M, Ikeguchi M, Kidera A, Suetake I, Arita K, Nakanishi M. Ishiyama S, et al. Among authors: nishiyama a. Mol Cell. 2017 Oct 19;68(2):350-360.e7. doi: 10.1016/j.molcel.2017.09.037. Mol Cell. 2017. PMID: 29053958 Free article.
Enhanced processivity of Dnmt1 by monoubiquitinated histone H3.
Mishima Y, Brueckner L, Takahashi S, Kawakami T, Otani J, Shinohara A, Takeshita K, Garvilles RG, Watanabe M, Sakai N, Takeshima H, Nachtegael C, Nishiyama A, Nakanishi M, Arita K, Nakashima K, Hojo H, Suetake I. Mishima Y, et al. Among authors: nishiyama a. Genes Cells. 2020 Jan;25(1):22-32. doi: 10.1111/gtc.12732. Epub 2019 Dec 3. Genes Cells. 2020. PMID: 31680384 Free article.
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
Nishiyama A, Mulholland CB, Bultmann S, Kori S, Endo A, Saeki Y, Qin W, Trummer C, Chiba Y, Yokoyama H, Kumamoto S, Kawakami T, Hojo H, Nagae G, Aburatani H, Tanaka K, Arita K, Leonhardt H, Nakanishi M. Nishiyama A, et al. Nat Commun. 2020 Mar 6;11(1):1222. doi: 10.1038/s41467-020-15006-4. Nat Commun. 2020. PMID: 32144273 Free PMC article.
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals.
Mulholland CB, Nishiyama A, Ryan J, Nakamura R, Yiğit M, Glück IM, Trummer C, Qin W, Bartoschek MD, Traube FR, Parsa E, Ugur E, Modic M, Acharya A, Stolz P, Ziegenhain C, Wierer M, Enard W, Carell T, Lamb DC, Takeda H, Nakanishi M, Bultmann S, Leonhardt H. Mulholland CB, et al. Among authors: nishiyama a. Nat Commun. 2020 Nov 24;11(1):5972. doi: 10.1038/s41467-020-19603-1. Nat Commun. 2020. PMID: 33235224 Free PMC article.
1,250 results