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Page 1
Accelerated osteocyte senescence and skeletal fragility in mice with type 2 diabetes.
Eckhardt BA, Rowsey JL, Thicke BS, Fraser DG, O'Grady KL, Bondar OP, Hines JM, Singh RJ, Thoreson AR, Rakshit K, Lagnado AB, Passos JF, Vella A, Matveyenko AV, Khosla S, Monroe DG, Farr JN. Eckhardt BA, et al. Among authors: rowsey jl. JCI Insight. 2020 May 7;5(9):e135236. doi: 10.1172/jci.insight.135236. JCI Insight. 2020. PMID: 32267250 Free PMC article.
Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice.
Doolittle ML, Saul D, Kaur J, Rowsey JL, Eckhardt B, Vos S, Grain S, Kroupova K, Ruan M, Weivoda M, Oursler MJ, Farr JN, Monroe DG, Khosla S. Doolittle ML, et al. Among authors: rowsey jl. J Bone Miner Res. 2022 Sep;37(9):1750-1760. doi: 10.1002/jbmr.4644. Epub 2022 Jul 22. J Bone Miner Res. 2022. PMID: 35789113 Free PMC article.
Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton.
Doolittle ML, Saul D, Kaur J, Rowsey JL, Vos SJ, Pavelko KD, Farr JN, Monroe DG, Khosla S. Doolittle ML, et al. Among authors: rowsey jl. bioRxiv [Preprint]. 2023 Jan 13:2023.01.12.523760. doi: 10.1101/2023.01.12.523760. bioRxiv. 2023. Update in: Nat Commun. 2023 Jul 31;14(1):4587. doi: 10.1038/s41467-023-40393-9 PMID: 36711531 Free PMC article. Updated. Preprint.
Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.
Farr JN, Saul D, Doolittle ML, Kaur J, Rowsey JL, Vos SJ, Froemming MN, Lagnado AB, Zhu Y, Weivoda M, Ikeno Y, Pignolo RJ, Niedernhofer LJ, Robbins PD, Jurk D, Passos JF, LeBrasseur NK, Tchkonia T, Kirkland JL, Monroe DG, Khosla S. Farr JN, et al. Among authors: rowsey jl. J Clin Invest. 2023 Apr 17;133(8):e162519. doi: 10.1172/JCI162519. J Clin Invest. 2023. PMID: 36809340 Free PMC article.
15 results