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Page 1
Language model-guided anticipation and discovery of unknown metabolites.
Qiang H, Wang F, Lu W, Xing X, Kim H, Merette SAM, Ayres LB, Oler E, AbuSalim JE, Roichman A, Neinast M, Cordova RA, Lee WD, Herbst E, Gupta V, Neff S, Hiebert-Giesbrecht M, Young A, Gautam V, Tian S, Wang B, Röst H, Greiner R, Chen L, Johnston CW, Foster LJ, Shapiro AM, Wishart DS, Rabinowitz JD, Skinnider MA. Qiang H, et al. Among authors: rabinowitz jd. bioRxiv [Preprint]. 2024 Nov 15:2024.11.13.623458. doi: 10.1101/2024.11.13.623458. bioRxiv. 2024. PMID: 39605668 Free PMC article. Preprint.
Quantification of nutrient fluxes during acute exercise in mice.
Axsom J, TeSlaa T, Lee WD, Chu Q, Cowan A, Bornstein MR, Neinast MD, Bartman CR, Blair MC, Li K, Thorsheim C, Rabinowitz JD, Arany Z. Axsom J, et al. Among authors: rabinowitz jd. Cell Metab. 2024 Oct 11:S1550-4131(24)00374-7. doi: 10.1016/j.cmet.2024.09.010. Online ahead of print. Cell Metab. 2024. PMID: 39413791
Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.
Doan KV, Luongo TS, Ts'olo TT, Lee WD, Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker N, Blair MC, Bye N, Davis JG, Holman CD, Chu Q, Wang L, Rabinowitz JD, Kelly DP, Cappola TP, Margulies KB, Baur JA. Doan KV, et al. Among authors: rabinowitz jd. Nat Cardiovasc Res. 2024 Oct;3(10):1236-1248. doi: 10.1038/s44161-024-00542-9. Epub 2024 Sep 18. Nat Cardiovasc Res. 2024. PMID: 39294272
A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism.
Hajihassani O, Zarei M, Roichman A, Loftus A, Boutros CS, Hue J, Naji P, Boyer J, Tahan S, Gallagher P, Beegan W, Choi J, Lei S, Kim C, Rathore M, Nakazzi F, Shah I, Lebo K, Cheng H, Mudigonda A, Alibeckoff S, Ji K, Graor H, Miyagi M, Vaziri-Gohar A, Brunengraber H, Wang R, Lund PJ, Rothermel LD, Rabinowitz JD, Winter JM. Hajihassani O, et al. Among authors: rabinowitz jd. bioRxiv [Preprint]. 2024 Jul 23:2024.07.19.604377. doi: 10.1101/2024.07.19.604377. bioRxiv. 2024. PMID: 39211182 Free PMC article. Preprint.
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Minhas PS, Jones JR, Latif-Hernandez A, Sugiura Y, Durairaj AS, Wang Q, Mhatre SD, Uenaka T, Crapser J, Conley T, Ennerfelt H, Jung YJ, Liu L, Prasad P, Jenkins BC, Ay YA, Matrongolo M, Goodman R, Newmeyer T, Heard K, Kang A, Wilson EN, Yang T, Ullian EM, Serrano GE, Beach TG, Wernig M, Rabinowitz JD, Suematsu M, Longo FM, McReynolds MR, Gage FH, Andreasson KI. Minhas PS, et al. Among authors: rabinowitz jd. Science. 2024 Aug 23;385(6711):eabm6131. doi: 10.1126/science.abm6131. Epub 2024 Aug 23. Science. 2024. PMID: 39172838
NAD+ precursors prolong survival and improve cardiac phenotypes in a mouse model of Friedreich's Ataxia.
Perry CE, Halawani SM, Mukherjee S, Ngaba LV, Lieu M, Lee WD, Davis JG, Adzika GK, Bebenek AN, Bazianos DD, Chen B, Mercado-Ayon E, Flatley LP, Suryawanshi AP, Ho I, Rabinowitz JD, Serai SD, Biko DM, Tamaroff J, DeDio A, Wade K, Lin KY, Livingston DJ, McCormack SE, Lynch DR, Baur JA. Perry CE, et al. Among authors: rabinowitz jd. JCI Insight. 2024 Jul 18;9(16):e177152. doi: 10.1172/jci.insight.177152. JCI Insight. 2024. PMID: 39171530 Free PMC article.
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Minhas PS, Jones JR, Latif-Hernandez A, Sugiura Y, Durairaj AS, Uenaka T, Wang Q, Mhatre SD, Liu L, Conley T, Ennerfelt H, Jung YJ, Prasad P, Jenkins BC, Goodman R, Newmeyer T, Heard K, Kang A, Wilson EN, Ullian EM, Serrano GE, Beach TG, Rabinowitz JD, Wernig M, Suematsu M, Longo FM, McReynolds MR, Gage FH, Andreasson KI. Minhas PS, et al. Among authors: rabinowitz jd. bioRxiv [Preprint]. 2024 Jun 28:2024.06.23.598940. doi: 10.1101/2024.06.23.598940. bioRxiv. 2024. Update in: Science. 2024 Aug 23;385(6711):eabm6131. doi: 10.1126/science.abm6131 PMID: 38979192 Free PMC article. Updated. Preprint.
307 results