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Host defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism.
Jekhmane S, Derks MGN, Maity S, Slingerland CJ, Tehrani KHME, Medeiros-Silva J, Charitou V, Ammerlaan D, Fetz C, Consoli NA, Cochrane RVK, Matheson EJ, van der Weijde M, Elenbaas BOW, Lavore F, Cox R, Lorent JH, Baldus M, Künzler M, Lelli M, Cochrane SA, Martin NI, Roos WH, Breukink E, Weingarth M. Jekhmane S, et al. Among authors: medeiros silva j. Nat Microbiol. 2024 Jul;9(7):1778-1791. doi: 10.1038/s41564-024-01696-9. Epub 2024 May 23. Nat Microbiol. 2024. PMID: 38783023 Free PMC article.
Atomic structure of the open SARS-CoV-2 E viroporin.
Medeiros-Silva J, Dregni AJ, Somberg NH, Duan P, Hong M. Medeiros-Silva J, et al. Sci Adv. 2023 Oct 13;9(41):eadi9007. doi: 10.1126/sciadv.adi9007. Epub 2023 Oct 13. Sci Adv. 2023. PMID: 37831764 Free PMC article.
SARS-CoV-2 Envelope Protein Forms Clustered Pentamers in Lipid Bilayers.
Somberg NH, Wu WW, Medeiros-Silva J, Dregni AJ, Jo H, DeGrado WF, Hong M. Somberg NH, et al. Among authors: medeiros silva j. Biochemistry. 2022 Nov 1;61(21):2280-2294. doi: 10.1021/acs.biochem.2c00464. Epub 2022 Oct 11. Biochemistry. 2022. PMID: 36219675 Free PMC article.
Specific Lipid Studies in Complex Membranes by Solid-State NMR Spectroscopy.
van Beekveld RAM, Derks MGN, Kumar R, Smid L, Maass T, Medeiros-Silva J, Breukink E, Weingarth M. van Beekveld RAM, et al. Among authors: medeiros silva j. Chemistry. 2022 Dec 15;28(70):e202202472. doi: 10.1002/chem.202202472. Epub 2022 Oct 25. Chemistry. 2022. PMID: 36098094 Free PMC article.
Teixobactin kills bacteria by a two-pronged attack on the cell envelope.
Shukla R, Lavore F, Maity S, Derks MGN, Jones CR, Vermeulen BJA, Melcrová A, Morris MA, Becker LM, Wang X, Kumar R, Medeiros-Silva J, van Beekveld RAM, Bonvin AMJJ, Lorent JH, Lelli M, Nowick JS, MacGillavry HD, Peoples AJ, Spoering AL, Ling LL, Hughes DE, Roos WH, Breukink E, Lewis K, Weingarth M. Shukla R, et al. Among authors: medeiros silva j. Nature. 2022 Aug;608(7922):390-396. doi: 10.1038/s41586-022-05019-y. Epub 2022 Aug 3. Nature. 2022. PMID: 35922513 Free PMC article.
26 results