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Page 1
Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PLpro).
Taylor AJ, Amporndanai K, Rietz TA, Zhao B, Thiruvaipati A, Wei Q, South TM, Crow MM, Apakama C, Sensintaffar JL, Phan J, Lee T, Fesik SW. Taylor AJ, et al. Among authors: amporndanai k. ACS Med Chem Lett. 2024 Jul 23;15(8):1351-1357. doi: 10.1021/acsmedchemlett.4c00238. eCollection 2024 Aug 8. ACS Med Chem Lett. 2024. PMID: 39140055 Free PMC article.
Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors.
Teuscher KB, Mills JJ, Tian J, Han C, Meyers KM, Sai J, South TM, Crow MM, Van Meveren M, Sensintaffar JL, Zhao B, Amporndanai K, Moore WJ, Stott GM, Tansey WP, Lee T, Fesik SW. Teuscher KB, et al. Among authors: amporndanai k. J Med Chem. 2023 Dec 28;66(24):16783-16806. doi: 10.1021/acs.jmedchem.3c01529. Epub 2023 Dec 12. J Med Chem. 2023. PMID: 38085679
Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites.
McPhillie MJ, Zhou Y, Hickman MR, Gordon JA, Weber CR, Li Q, Lee PJ, Amporndanai K, Johnson RM, Darby H, Woods S, Li ZH, Priestley RS, Ristroph KD, Biering SB, El Bissati K, Hwang S, Hakim FE, Dovgin SM, Lykins JD, Roberts L, Hargrave K, Cong H, Sinai AP, Muench SP, Dubey JP, Prud'homme RK, Lorenzi HA, Biagini GA, Moreno SN, Roberts CW, Antonyuk SV, Fishwick CWG, McLeod R. McPhillie MJ, et al. Among authors: amporndanai k. Front Cell Infect Microbiol. 2020 Jun 9;10:203. doi: 10.3389/fcimb.2020.00203. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32626661 Free PMC article.
Potent Antimalarial 2-Pyrazolyl Quinolone bc 1 (Qi) Inhibitors with Improved Drug-like Properties.
David Hong W, Leung SC, Amporndanai K, Davies J, Priestley RS, Nixon GL, Berry NG, Samar Hasnain S, Antonyuk S, Ward SA, Biagini GA, O'Neill PM. David Hong W, et al. Among authors: amporndanai k. ACS Med Chem Lett. 2018 Oct 19;9(12):1205-1210. doi: 10.1021/acsmedchemlett.8b00371. eCollection 2018 Dec 13. ACS Med Chem Lett. 2018. PMID: 30613327 Free PMC article.
11 results