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Distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia.
Markov NS, Ren Z, Senkow KJ, Grant RA, Gao CA, Malsin ES, Sichizya L, Kihshen H, Helmin KA, Jovisic M, Arnold JM, Pérez-Leonor XG, Abdala-Valencia H, Swaminathan S, Nwaezeapu J, Kang M, Rasmussen L, Ozer EA, Lorenzo-Redondo R, Hultquist JF, Simons LM, Rios-Guzman E, Misharin AV, Wunderink RG, Budinger GRS, Singer BD, Morales-Nebreda L; NU SCRIPT Study Investigators. Markov NS, et al. Among authors: singer bd. Nat Immunol. 2024 Sep;25(9):1607-1622. doi: 10.1038/s41590-024-01914-w. Epub 2024 Aug 13. Nat Immunol. 2024. PMID: 39138384
Transcriptomic signatures decode Th17 cell pathogenicity.
Reyfman PA, Bartom ET, Singer BD. Reyfman PA, et al. Among authors: singer bd. Cell Mol Immunol. 2016 Sep;13(5):557-9. doi: 10.1038/cmi.2016.22. Epub 2016 May 2. Cell Mol Immunol. 2016. PMID: 27133470 Free PMC article. No abstract available.
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span.
Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Gates K, Lam AP, Nicholson TT, Homan PJ, Soberanes S, Dominguez S, Morgan VK, Saber R, Shaffer A, Hinchcliff M, Marshall SA, Bharat A, Berdnikovs S, Bhorade SM, Bartom ET, Morimoto RI, Balch WE, Sznajder JI, Chandel NS, Mutlu GM, Jain M, Gottardi CJ, Singer BD, Ridge KM, Bagheri N, Shilatifard A, Budinger GRS, Perlman H. Misharin AV, et al. Among authors: singer bd. J Exp Med. 2017 Aug 7;214(8):2387-2404. doi: 10.1084/jem.20162152. Epub 2017 Jul 10. J Exp Med. 2017. PMID: 28694385 Free PMC article.
Metastatic pulmonary calcification and end-stage renal disease.
Walter JM, Stanley M, Singer BD. Walter JM, et al. Among authors: singer bd. Cleve Clin J Med. 2017 Sep;84(9):668-669. doi: 10.3949/ccjm.84a.16132. Cleve Clin J Med. 2017. PMID: 28885910 Free PMC article. No abstract available.
DNA methylation regulates the neonatal CD4+ T-cell response to pneumonia in mice.
McGrath-Morrow SA, Ndeh R, Helmin KA, Chen SY, Anekalla KR, Abdala-Valencia H, D'Alessio FR, Collaco JM, Singer BD. McGrath-Morrow SA, et al. Among authors: singer bd. J Biol Chem. 2018 Jul 27;293(30):11772-11783. doi: 10.1074/jbc.RA118.003589. Epub 2018 Jun 4. J Biol Chem. 2018. PMID: 29866884 Free PMC article.
DNA methylation as a transcriptional regulator of the immune system.
Morales-Nebreda L, McLafferty FS, Singer BD. Morales-Nebreda L, et al. Among authors: singer bd. Transl Res. 2019 Feb;204:1-18. doi: 10.1016/j.trsl.2018.08.001. Epub 2018 Aug 9. Transl Res. 2019. PMID: 30170004 Free PMC article. Review.
112 results