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PheMIME: an interactive web app and knowledge base for phenome-wide, multi-institutional multimorbidity analysis.
Zhang S, Strayer N, Vessels T, Choi K, Wang GW, Li Y, Bejan CA, Hsi RS, Bick AG, Velez Edwards DR, Savona MR, Phillips EJ, Pulley JM, Self WH, Hopkins WC, Roden DM, Smoller JW, Ruderfer DM, Xu Y. Zhang S, et al. Among authors: savona mr. J Am Med Inform Assoc. 2024 Nov 1;31(11):2440-2446. doi: 10.1093/jamia/ocae182. J Am Med Inform Assoc. 2024. PMID: 39127052 Free PMC article.
Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs.
Strayer N, Zhang S, Yao L, Vessels T, Bejan CA, Hsi RS, Shirey-Rice JK, Balko JM, Johnson DB, Phillips EJ, Bick A, Edwards TL, Velez Edwards DR, Pulley JM, Wells QS, Savona MR, Cox NJ, Roden DM, Ruderfer DM, Xu Y. Strayer N, et al. Among authors: savona mr. Bioinformatics. 2023 Jan 1;39(1):btac780. doi: 10.1093/bioinformatics/btac780. Bioinformatics. 2023. PMID: 36472455 Free PMC article.
PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis.
Zhang S, Strayer N, Vessels T, Choi K, Wang GW, Li Y, Bejan CA, Hsi RS, Bick AG, Velez Edwards DR, Savona MR, Philips EJ, Pulley J, Self WH, Hopkins WC, Roden DM, Smoller JW, Ruderfer DM, Xu Y. Zhang S, et al. Among authors: savona mr. medRxiv [Preprint]. 2023 Jul 30:2023.07.23.23293047. doi: 10.1101/2023.07.23.23293047. medRxiv. 2023. Update in: J Am Med Inform Assoc. 2024 Nov 1;31(11):2440-2446. doi: 10.1093/jamia/ocae182. PMID: 37547012 Free PMC article. Updated. Preprint.
Driver mutation zygosity is a critical factor in predicting clonal hematopoiesis transformation risk.
Kishtagari A, Khan MAW, Li Y, Vlasschaert C, Marneni N, Silver AJ, von Beck K, Spaulding T, Stockton S, Snider C, Sochacki A, Dorand D, Mack TM, Ferrell PB Jr, Xu Y, Bejan CA, Savona MR, Bick AG. Kishtagari A, et al. Among authors: savona mr. Blood Cancer J. 2024 Jan 15;14(1):6. doi: 10.1038/s41408-023-00974-9. Blood Cancer J. 2024. PMID: 38225345 Free PMC article.
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation.
Heimlich JB, Bhat P, Parker AC, Jenkins MT, Vlasschaert C, Ulloa J, Van Amburg JC, Potts CR, Olson S, Silver AJ, Ahmad A, Sharber B, Brown D, Hu N, van Galen P, Savona MR, Bick AG, Ferrell PB. Heimlich JB, et al. Among authors: savona mr. Blood Adv. 2024 Jul 23;8(14):3665-3678. doi: 10.1182/bloodadvances.2023011445. Blood Adv. 2024. PMID: 38507736 Free PMC article.
Cost-Effective and Scalable Clonal Hematopoiesis Assay Provides Insight into Clonal Dynamics.
Mack T, Vlasschaert C, von Beck K, Silver AJ, Heimlich JB, Poisner H, Condon HR, Ulloa J, Sochacki AL, Spaulding TP, Kishtagari A, Bejan CA, Xu Y, Savona MR, Jones A, Bick AG. Mack T, et al. Among authors: savona mr. J Mol Diagn. 2024 Jul;26(7):563-573. doi: 10.1016/j.jmoldx.2024.03.007. Epub 2024 Apr 6. J Mol Diagn. 2024. PMID: 38588769 Free article.
Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository.
Shannon ML, Heimlich JB, Olson S, Debevec A, Copeland Z, Kishtagari A, Vlasschaert C, Snider C, Silver AJ, Brown D, Spaulding T, Bhatta M, Pugh K, Stockton SS, Ulloa J, Xu Y, Baljevic M, Moslehi J, Jahangir E, Ferrell PB, Slosky D, Bick AG, Savona MR. Shannon ML, et al. Among authors: savona mr. Blood Adv. 2024 Jul 9;8(13):3453-3463. doi: 10.1182/bloodadvances.2023011510. Blood Adv. 2024. PMID: 38608257 Free PMC article.
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.
Howard GC, Wang J, Rose KL, Jones C, Patel P, Tsui T, Florian AC, Vlach L, Lorey SL, Grieb BC, Smith BN, Slota MJ, Reynolds EM, Goswami S, Savona MR, Mason FM, Lee T, Fesik S, Liu Q, Tansey WP. Howard GC, et al. Among authors: savona mr. Elife. 2024 Apr 29;12:RP90683. doi: 10.7554/eLife.90683. Elife. 2024. PMID: 38682900 Free PMC article.
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition.
Howard GC, Wang J, Rose KL, Jones C, Patel P, Tsui T, Florian AC, Vlach L, Lorey SL, Grieb BC, Smith BN, Slota MJ, Reynolds EM, Goswami S, Savona MR, Mason FM, Lee T, Fesik SW, Liu Q, Tansey WP. Howard GC, et al. Among authors: savona mr. bioRxiv [Preprint]. 2024 Jan 10:2023.07.26.550648. doi: 10.1101/2023.07.26.550648. bioRxiv. 2024. Update in: Elife. 2024 Apr 29;12:RP90683. doi: 10.7554/eLife.90683. PMID: 37546802 Free PMC article. Updated. Preprint.
154 results