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A synthetic peptide mimic kills Candida albicans and synergistically prevents infection.
Schaefer S, Vij R, Sprague JL, Austermeier S, Dinh H, Judzewitsch PR, Müller-Loennies S, Lopes Silva T, Seemann E, Qualmann B, Hertweck C, Scherlach K, Gutsmann T, Cain AK, Corrigan N, Gresnigt MS, Boyer C, Lenardon MD, Brunke S. Schaefer S, et al. Among authors: austermeier s. Nat Commun. 2024 Aug 9;15(1):6818. doi: 10.1038/s41467-024-50491-x. Nat Commun. 2024. PMID: 39122699 Free PMC article.
Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation.
Jaeger M, Dietschmann A, Austermeier S, Dinçer S, Porschitz P, Vornholz L, Maas RJA, Sprenkeler EGG, Ruland J, Wirtz S, Azam T, Joosten LAB, Hube B, Netea MG, Dinarello CA, Gresnigt MS. Jaeger M, et al. Among authors: austermeier s. Virulence. 2024 Dec;15(1):2333367. doi: 10.1080/21505594.2024.2333367. Epub 2024 Apr 10. Virulence. 2024. PMID: 38515333 Free PMC article.