Tan TK - Search Results

1

Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma.

Xiong S, Zhou J, Tan TK, Chung TH, Tan TZ, Toh SH, Tang NXN, Jia Y, See YX, Fullwood MJ, Sanda T, Chng WJ. Xiong S, et al. Among authors: tan tk. Nat Commun. 2024 Aug 9;15(1):6810. doi: 10.1038/s41467-024-50910-z. Nat Commun. 2024. PMID: 39122682 Free PMC article.

2

Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma.

Jia Y, Zhou J, Tan TK, Chung TH, Chen Y, Chooi JY, Sanda T, Fullwood MJ, Xiong S, Toh SHM, Balan K, Wong RWJ, Lim JSL, Zhang E, Cai Z, Shen P, Chng WJ. Jia Y, et al. Among authors: tan tk. Cancer Res. 2022 Feb 1;82(3):406-418. doi: 10.1158/0008-5472.CAN-21-0921. Epub 2021 Dec 10. Cancer Res. 2022. PMID: 34893510 Free PMC article.

3

Super-enhancer-driven TOX2 mediates oncogenesis in Natural Killer/T Cell Lymphoma.

Zhou J, Toh SH, Tan TK, Balan K, Lim JQ, Tan TZ, Xiong S, Jia Y, Ng SB, Peng Y, Jeyasekharan AD, Fan S, Lim ST, Ong CJ, Ong CK, Sanda T, Chng WJ. Zhou J, et al. Among authors: tan tk, tan tz. Mol Cancer. 2023 Apr 10;22(1):69. doi: 10.1186/s12943-023-01767-1. Mol Cancer. 2023. PMID: 37032358 Free PMC article.

4

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia.

Tan SH, Leong WZ, Ngoc PCT, Tan TK, Bertulfo FC, Lim MC, An O, Li Z, Yeoh AEJ, Fullwood MJ, Tenen DG, Sanda T. Tan SH, et al. Among authors: tan tk. Blood. 2019 Jul 18;134(3):239-251. doi: 10.1182/blood.2018874503. Epub 2019 May 10. Blood. 2019. PMID: 31076442 Free PMC article.

5

ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry.

Wang L, Tan TK, Durbin AD, Zimmerman MW, Abraham BJ, Tan SH, Ngoc PCT, Weichert-Leahey N, Akahane K, Lawton LN, Rokita JL, Maris JM, Young RA, Look AT, Sanda T. Wang L, et al. Among authors: tan tk, tan sh. Nat Commun. 2019 Dec 9;10(1):5622. doi: 10.1038/s41467-019-13515-5. Nat Commun. 2019. PMID: 31819055 Free PMC article.

6

Myeloma-specific superenhancers affect genes of biological and clinical relevance in myeloma.

Jia Y, Zhou J, Tan TK, Chung TH, Wong RWJ, Chooi JY, Lim JSL, Sanda T, Ooi M, De Mel S, Soekojo C, Chen Y, Zhang E, Cai Z, Shen P, Ruan J, Chng WJ. Jia Y, et al. Among authors: tan tk. Blood Cancer J. 2021 Feb 12;11(2):32. doi: 10.1038/s41408-021-00421-7. Blood Cancer J. 2021. PMID: 33579893 Free PMC article.

7

IRF4 drives clonal evolution and lineage choice in a zebrafish model of T-cell lymphoma.

Amanda S, Tan TK, Ong JZL, Theardy MS, Wong RWJ, Huang XZ, Ali MZ, Li Y, Gong Z, Inagaki H, Foo EY, Pang B, Tan SY, Iida S, Sanda T. Amanda S, et al. Among authors: tan tk, tan sy. Nat Commun. 2022 May 3;13(1):2420. doi: 10.1038/s41467-022-30053-9. Nat Commun. 2022. PMID: 35504924 Free PMC article.

8

Regulatory mechanisms and context-dependent roles of TAL1 in T-cell acute lymphoblastic leukemia.

Ong JZL, Tan TK, Wang L, Tan SH, Sanda T. Ong JZL, et al. Among authors: tan tk, tan sh. Haematologica. 2024 May 1;109(5):1359-1372. doi: 10.3324/haematol.2023.283450. Haematologica. 2024. PMID: 37855064 Free PMC article.

9

Oncogenic transcriptional program driven by TAL1 in T-cell acute lymphoblastic leukemia.

Tan TK, Zhang C, Sanda T. Tan TK, et al. Int J Hematol. 2019 Jan;109(1):5-17. doi: 10.1007/s12185-018-2518-z. Epub 2018 Aug 25. Int J Hematol. 2019. PMID: 30145780 Review.

10

A Myb enhancer-guided analysis of basophil and mast cell differentiation.

Matsumura T, Totani H, Gunji Y, Fukuda M, Yokomori R, Deng J, Rethnam M, Yang C, Tan TK, Karasawa T, Kario K, Takahashi M, Osato M, Sanda T, Suda T. Matsumura T, et al. Among authors: tan tk. Nat Commun. 2022 Nov 18;13(1):7064. doi: 10.1038/s41467-022-34906-1. Nat Commun. 2022. PMID: 36400777 Free PMC article.

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