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Discovery of Novel Haloalkane Dehalogenase Inhibitors.
Buryska T, Daniel L, Kunka A, Brezovsky J, Damborsky J, Prokop Z. Buryska T, et al. Among authors: damborsky j. Appl Environ Microbiol. 2016 Jan 15;82(6):1958-1965. doi: 10.1128/AEM.03916-15. Appl Environ Microbiol. 2016. PMID: 26773086 Free PMC article.
Haloalkane Dehalogenases From Marine Organisms.
Kunka A, Damborsky J, Prokop Z. Kunka A, et al. Among authors: damborsky j. Methods Enzymol. 2018;605:203-251. doi: 10.1016/bs.mie.2018.03.005. Epub 2018 May 28. Methods Enzymol. 2018. PMID: 29909825 Review.
Molecular Gating of an Engineered Enzyme Captured in Real Time.
Kokkonen P, Sykora J, Prokop Z, Ghose A, Bednar D, Amaro M, Beerens K, Bidmanova S, Slanska M, Brezovsky J, Damborsky J, Hof M. Kokkonen P, et al. Among authors: damborsky j. J Am Chem Soc. 2018 Dec 26;140(51):17999-18008. doi: 10.1021/jacs.8b09848. Epub 2018 Dec 14. J Am Chem Soc. 2018. PMID: 30501200
Engineering enzyme access tunnels.
Kokkonen P, Bednar D, Pinto G, Prokop Z, Damborsky J. Kokkonen P, et al. Among authors: damborsky j. Biotechnol Adv. 2019 Nov 1;37(6):107386. doi: 10.1016/j.biotechadv.2019.04.008. Epub 2019 Apr 23. Biotechnol Adv. 2019. PMID: 31026496 Free article. Review.
The impact of tunnel mutations on enzymatic catalysis depends on the tunnel-substrate complementarity and the rate-limiting step.
Kokkonen P, Slanska M, Dockalova V, Pinto GP, Sánchez-Carnerero EM, Damborsky J, Klán P, Prokop Z, Bednar D. Kokkonen P, et al. Among authors: damborsky j. Comput Struct Biotechnol J. 2020 Mar 25;18:805-813. doi: 10.1016/j.csbj.2020.03.017. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32308927 Free PMC article.
259 results