Green JP - Search Results

1

DNA-sensing inflammasomes cause recurrent atherosclerotic stroke.

Cao J, Roth S, Zhang S, Kopczak A, Mami S, Asare Y, Georgakis MK, Messerer D, Horn A, Shemer R, Jacqmarcq C, Picot A, Green JP, Schlegl C, Li X, Tomas L, Dutsch A, Liman TG, Endres M, Wernsdorf SR, Fürle C, Carofiglio O, Zhu J, Brough D; DEMDAS Study Group; Hornung V, Dichgans M, Vivien D, Schulz C, Dor Y, Tiedt S, Sager HB, Grosse GM, Liesz A. Cao J, et al. Among authors: green jp. Nature. 2024 Sep;633(8029):433-441. doi: 10.1038/s41586-024-07803-4. Epub 2024 Aug 7. Nature. 2024. PMID: 39112714 Free PMC article.

2

Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome.

Green JP, El-Sharkawy LY, Roth S, Zhu J, Cao J, Leach AG, Liesz A, Freeman S, Brough D. Green JP, et al. iScience. 2023 Apr 27;26(5):106758. doi: 10.1016/j.isci.2023.106758. eCollection 2023 May 19. iScience. 2023. PMID: 37216118 Free PMC article.

3

Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages.

Hoyle C, Green JP, Allan SM, Brough D, Lemarchand E. Hoyle C, et al. Among authors: green jp. Immunology. 2022 Apr;165(4):460-480. doi: 10.1111/imm.13454. Epub 2022 Mar 2. Immunology. 2022. PMID: 35137954 Free PMC article.

4

The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome.

Gleeson TA, Kaiser C, Lawrence CB, Brough D, Allan SM, Green JP. Gleeson TA, et al. Among authors: green jp. bioRxiv [Preprint]. 2024 Mar 1:2024.02.27.582284. doi: 10.1101/2024.02.27.582284. bioRxiv. 2024. Update in: Dis Model Mech. 2024 Jul 1;17(7):dmm050762. doi: 10.1242/dmm.050762. PMID: 38464243 Free PMC article. Updated. Preprint.

5

Looking into the IL-1 of the storm: are inflammasomes the link between immunothrombosis and hyperinflammation in cytokine storm syndromes?

Gleeson TA, Nordling E, Kaiser C, Lawrence CB, Brough D, Green JP, Allan SM. Gleeson TA, et al. Among authors: green jp. Discov Immunol. 2022 Sep 14;1(1):kyac005. doi: 10.1093/discim/kyac005. eCollection 2022. Discov Immunol. 2022. PMID: 38566906 Free PMC article. Review.

6

The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome.

Gleeson TA, Kaiser C, Lawrence CB, Brough D, Allan SM, Green JP. Gleeson TA, et al. Among authors: green jp. Dis Model Mech. 2024 Jul 1;17(7):dmm050762. doi: 10.1242/dmm.050762. Epub 2024 Jul 30. Dis Model Mech. 2024. PMID: 38775430 Free PMC article.

7

Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions.

Wellens R, Tapia VS, Seoane PI, Bennett H, Adamson A, Coutts G, Rivers-Auty J, Lowe M, Green JP, Lopez-Castejon G, Brough D, Hoyle C. Wellens R, et al. Among authors: green jp. Nat Commun. 2024 Aug 8;15(1):6750. doi: 10.1038/s41467-024-50901-0. Nat Commun. 2024. PMID: 39117622 Free PMC article.

8

Mechanisms of NLRP3 priming in inflammaging and age related diseases.

Gritsenko A, Green JP, Brough D, Lopez-Castejon G. Gritsenko A, et al. Among authors: green jp. Cytokine Growth Factor Rev. 2020 Oct;55:15-25. doi: 10.1016/j.cytogfr.2020.08.003. Epub 2020 Aug 24. Cytokine Growth Factor Rev. 2020. PMID: 32883606 Free PMC article. Review.

9

LRRC8A is dispensable for a variety of microglial functions and response to acute stroke.

Cook JR, Gray AL, Lemarchand E, Schiessl I, Green JP, Newland MC, Dyer DP, Brough D, Lawrence CB. Cook JR, et al. Among authors: green jp. Glia. 2022 Jun;70(6):1068-1083. doi: 10.1002/glia.24156. Epub 2022 Feb 12. Glia. 2022. PMID: 35150591 Free PMC article.

10

Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification.

Yu S, Green J, Wellens R, Lopez-Castejon G, Brough D. Yu S, et al. FEBS J. 2021 May;288(10):3186-3196. doi: 10.1111/febs.15619. Epub 2020 Nov 21. FEBS J. 2021. PMID: 33145969 Free PMC article.

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