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The ribosome lowers the entropic penalty of protein folding.
Streit JO, Bukvin IV, Chan SHS, Bashir S, Woodburn LF, Włodarski T, Figueiredo AM, Jurkeviciute G, Sidhu HK, Hornby CR, Waudby CA, Cabrita LD, Cassaignau AME, Christodoulou J. Streit JO, et al. Among authors: waudby ca. Nature. 2024 Sep;633(8028):232-239. doi: 10.1038/s41586-024-07784-4. Epub 2024 Aug 7. Nature. 2024. PMID: 39112704 Free PMC article.
Protein folding on the ribosome studied using NMR spectroscopy.
Waudby CA, Launay H, Cabrita LD, Christodoulou J. Waudby CA, et al. Prog Nucl Magn Reson Spectrosc. 2013 Oct;74(100):57-75. doi: 10.1016/j.pnmrs.2013.07.003. Epub 2013 Jul 27. Prog Nucl Magn Reson Spectrosc. 2013. PMID: 24083462 Free PMC article. Review.
The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.
Porcari R, Proukakis C, Waudby CA, Bolognesi B, Mangione PP, Paton JF, Mullin S, Cabrita LD, Penco A, Relini A, Verona G, Vendruscolo M, Stoppini M, Tartaglia GG, Camilloni C, Christodoulou J, Schapira AH, Bellotti V. Porcari R, et al. Among authors: waudby ca. J Biol Chem. 2015 Jan 23;290(4):2395-404. doi: 10.1074/jbc.M114.610527. Epub 2014 Dec 10. J Biol Chem. 2015. PMID: 25505181 Free PMC article.
59 results