Zhu C - Search Results

1

A therapeutic small molecule enhances γ-oscillations and improves cognition/memory in Alzheimer's disease model mice.

Wei X, Campagna JJ, Jagodzinska B, Wi D, Cohn W, Lee JT, Zhu C, Huang CS, Molnár L, Houser CR, John V, Mody I. Wei X, et al. Among authors: zhu c. Proc Natl Acad Sci U S A. 2024 Aug 13;121(33):e2400420121. doi: 10.1073/pnas.2400420121. Epub 2024 Aug 6. Proc Natl Acad Sci U S A. 2024. PMID: 39106304 Free PMC article.

2

A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.

Campagna J, Spilman P, Jagodzinska B, Bai D, Hatami A, Zhu C, Bilousova T, Jun M, Elias CJ, Pham J, Cole G, LaDu MJ, Jung ME, Bredesen DE, John V. Campagna J, et al. Among authors: zhu c. Sci Rep. 2018 Dec 4;8(1):17574. doi: 10.1038/s41598-018-35687-8. Sci Rep. 2018. PMID: 30514854 Free PMC article.

3

Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease.

Bilousova T, Simmons BJ, Knapp RR, Elias CJ, Campagna J, Melnik M, Chandra S, Focht S, Zhu C, Vadivel K, Jagodzinska B, Cohn W, Spilman P, Gylys KH, Garg NK, John V. Bilousova T, et al. Among authors: zhu c. ACS Chem Biol. 2020 Jun 19;15(6):1671-1684. doi: 10.1021/acschembio.0c00311. Epub 2020 May 14. ACS Chem Biol. 2020. PMID: 32352753 Free PMC article.

4

Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.

Zhu C, Bilousova T, Focht S, Jun M, Elias CJ, Melnik M, Chandra S, Campagna J, Cohn W, Hatami A, Spilman P, Gylys KH, John V. Zhu C, et al. Mol Brain. 2021 Apr 19;14(1):70. doi: 10.1186/s13041-021-00776-9. Mol Brain. 2021. PMID: 33875010 Free PMC article.

5

Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2.

Bilousova T, Elias C, Miyoshi E, Alam MP, Zhu C, Campagna J, Vadivel K, Jagodzinska B, Gylys KH, John V. Bilousova T, et al. Among authors: zhu c. Biochem Biophys Res Commun. 2018 May 23;499(4):751-757. doi: 10.1016/j.bbrc.2018.03.209. Epub 2018 Apr 9. Biochem Biophys Res Commun. 2018. PMID: 29604274 Free PMC article.

6

Correction to: Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.

Zhu C, Bilousova T, Focht S, Jun M, Elias CJ, Melnik M, Chandra S, Campagna J, Cohn W, Hatami A, Spilman P, Gylys KH, John V. Zhu C, et al. Mol Brain. 2021 Jul 8;14(1):108. doi: 10.1186/s13041-021-00816-4. Mol Brain. 2021. PMID: 34238327 Free PMC article. No abstract available.

7

Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures.

Cohn W, Melnik M, Huang C, Teter B, Chandra S, Zhu C, McIntire LB, John V, Gylys KH, Bilousova T. Cohn W, et al. Among authors: zhu c. Front Pharmacol. 2021 Dec 2;12:766082. doi: 10.3389/fphar.2021.766082. eCollection 2021. Front Pharmacol. 2021. PMID: 34925024 Free PMC article.

8

Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue.

Cohn W, Zhu C, Campagna J, Bilousova T, Spilman P, Teter B, Li F, Guo R, Elashoff D, Cole GM, Avidan A, Faull KF, Whitelegge J, Wong DTW, John V. Cohn W, et al. Among authors: zhu c. Int J Mol Sci. 2022 May 9;23(9):5257. doi: 10.3390/ijms23095257. Int J Mol Sci. 2022. PMID: 35563647 Free PMC article.

9

Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process.

Videlock EJ, Hatami A, Zhu C, Kawaguchi R, Chen H, Khan T, Yehya AHS, Stiles L, Joshi S, Hoffman JM, Law KM, Rankin CR, Chang L, Maidment NT, John V, Geschwind DH, Pothoulakis C. Videlock EJ, et al. Among authors: zhu c. J Parkinsons Dis. 2023;13(7):1127-1147. doi: 10.3233/JPD-223568. J Parkinsons Dis. 2023. PMID: 37638450 Free PMC article.

10

Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical.

Lee HJ, Zhang Y, Zhu C, Duff K, Pardridge WM. Lee HJ, et al. Among authors: zhu c. J Cereb Blood Flow Metab. 2002 Feb;22(2):223-31. doi: 10.1097/00004647-200202000-00010. J Cereb Blood Flow Metab. 2002. PMID: 11823720

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