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413 results

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Effect of antihypertensive deprescribing on hospitalisation and mortality: long-term follow-up of the OPTiMISE randomised controlled trial.
Sheppard JP, Temple E, Wang A, Smith A, Pollock S, Ford GA, Hobbs FDR, Kenealy N, Little P, Lown M, de Lusignan S, Mant J, McCartney D, Payne RA, Williams M, Yu LM, McManus RJ; OPTiMISE Investigators. Sheppard JP, et al. Among authors: yu lm. Lancet Healthy Longev. 2024 Aug;5(8):e563-e573. doi: 10.1016/S2666-7568(24)00131-4. Epub 2024 Jul 30. Lancet Healthy Longev. 2024. PMID: 39094592 Free PMC article. Clinical Trial.
Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind, randomised controlled pilot trial.
Freeman D, Waite F, Startup H, Myers E, Lister R, McInerney J, Harvey AG, Geddes J, Zaiwalla Z, Luengo-Fernandez R, Foster R, Clifton L, Yu LM. Freeman D, et al. Among authors: yu lm. Lancet Psychiatry. 2015 Nov;2(11):975-83. doi: 10.1016/S2215-0366(15)00314-4. Epub 2015 Sep 9. Lancet Psychiatry. 2015. PMID: 26363701 Free PMC article. Clinical Trial.
Telemonitoring and/or self-monitoring of blood pressure in hypertension (TASMINH4): protocol for a randomised controlled trial.
Franssen M, Farmer A, Grant S, Greenfield S, Heneghan C, Hobbs R, Hodgkinson J, Jowett S, Mant J, Martin U, Milner S, Monahan M, Ogburn E, Perera-Salazar R, Schwartz C, Yu LM, McManus RJ. Franssen M, et al. Among authors: yu lm. BMC Cardiovasc Disord. 2017 Feb 13;17(1):58. doi: 10.1186/s12872-017-0494-5. BMC Cardiovasc Disord. 2017. PMID: 28193176 Free PMC article. Clinical Trial.
The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis.
Freeman D, Sheaves B, Goodwin GM, Yu LM, Nickless A, Harrison PJ, Emsley R, Luik AI, Foster RG, Wadekar V, Hinds C, Gumley A, Jones R, Lightman S, Jones S, Bentall R, Kinderman P, Rowse G, Brugha T, Blagrove M, Gregory AM, Fleming L, Walklet E, Glazebrook C, Davies EB, Hollis C, Haddock G, John B, Coulson M, Fowler D, Pugh K, Cape J, Moseley P, Brown G, Hughes C, Obonsawin M, Coker S, Watkins E, Schwannauer M, MacMahon K, Siriwardena AN, Espie CA. Freeman D, et al. Among authors: yu lm. Lancet Psychiatry. 2017 Oct;4(10):749-758. doi: 10.1016/S2215-0366(17)30328-0. Epub 2017 Sep 6. Lancet Psychiatry. 2017. PMID: 28888927 Free PMC article. Clinical Trial.
Efficacy of self-monitored blood pressure, with or without telemonitoring, for titration of antihypertensive medication (TASMINH4): an unmasked randomised controlled trial.
McManus RJ, Mant J, Franssen M, Nickless A, Schwartz C, Hodgkinson J, Bradburn P, Farmer A, Grant S, Greenfield SM, Heneghan C, Jowett S, Martin U, Milner S, Monahan M, Mort S, Ogburn E, Perera-Salazar R, Shah SA, Yu LM, Tarassenko L, Hobbs FDR; TASMINH4 investigators. McManus RJ, et al. Among authors: yu lm. Lancet. 2018 Mar 10;391(10124):949-959. doi: 10.1016/S0140-6736(18)30309-X. Epub 2018 Feb 27. Lancet. 2018. PMID: 29499873 Free PMC article. Clinical Trial.
OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trial.
Sheppard JP, Burt J, Lown M, Temple E, Benson J, Ford GA, Heneghan C, Hobbs FDR, Jowett S, Little P, Mant J, Mollison J, Nickless A, Ogburn E, Payne R, Williams M, Yu LM, McManus RJ. Sheppard JP, et al. Among authors: yu lm. BMJ Open. 2018 Oct 4;8(9):e022930. doi: 10.1136/bmjopen-2018-022930. BMJ Open. 2018. PMID: 30287610 Free PMC article.
Blood pressure monitoring in high-risk pregnancy to improve the detection and monitoring of hypertension (the BUMP 1 and 2 trials): protocol for two linked randomised controlled trials.
Dougall G, Franssen M, Tucker KL, Yu LM, Hinton L, Rivero-Arias O, Abel L, Allen J, Band RJ, Chisholm A, Crawford C, Green M, Greenfield S, Hodgkinson J, Leeson P, McCourt C, MacKillop L, Nickless A, Sandall J, Santos M, Tarassenko L, Velardo C, Wilson H, Yardley L, Chappell L, McManus RJ. Dougall G, et al. Among authors: yu lm. BMJ Open. 2020 Jan 23;10(1):e034593. doi: 10.1136/bmjopen-2019-034593. BMJ Open. 2020. PMID: 31980512 Free PMC article. Clinical Trial.
Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients With Hypertension Aged 80 Years and Older: The OPTIMISE Randomized Clinical Trial.
Sheppard JP, Burt J, Lown M, Temple E, Lowe R, Fraser R, Allen J, Ford GA, Heneghan C, Hobbs FDR, Jowett S, Kodabuckus S, Little P, Mant J, Mollison J, Payne RA, Williams M, Yu LM, McManus RJ; OPTIMISE Investigators. Sheppard JP, et al. Among authors: yu lm. JAMA. 2020 May 26;323(20):2039-2051. doi: 10.1001/jama.2020.4871. JAMA. 2020. PMID: 32453368 Free PMC article. Clinical Trial.
413 results