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Effect of antihypertensive deprescribing on hospitalisation and mortality: long-term follow-up of the OPTiMISE randomised controlled trial.
Sheppard JP, Temple E, Wang A, Smith A, Pollock S, Ford GA, Hobbs FDR, Kenealy N, Little P, Lown M, de Lusignan S, Mant J, McCartney D, Payne RA, Williams M, Yu LM, McManus RJ; OPTiMISE Investigators. Sheppard JP, et al. Among authors: temple e. Lancet Healthy Longev. 2024 Aug;5(8):e563-e573. doi: 10.1016/S2666-7568(24)00131-4. Epub 2024 Jul 30. Lancet Healthy Longev. 2024. PMID: 39094592 Free PMC article. Clinical Trial.
Functional imaging and circulating biomarkers of response to regorafenib in treatment-refractory metastatic colorectal cancer patients in a prospective phase II study.
Khan K, Rata M, Cunningham D, Koh DM, Tunariu N, Hahne JC, Vlachogiannis G, Hedayat S, Marchetti S, Lampis A, Damavandi MD, Lote H, Rana I, Williams A, Eccles SA, Fontana E, Collins D, Eltahir Z, Rao S, Watkins D, Starling N, Thomas J, Kalaitzaki E, Fotiadis N, Begum R, Bali M, Rugge M, Temple E, Fassan M, Chau I, Braconi C, Valeri N. Khan K, et al. Among authors: temple e. Gut. 2018 Aug;67(8):1484-1492. doi: 10.1136/gutjnl-2017-314178. Epub 2017 Aug 8. Gut. 2018. PMID: 28790159 Free PMC article. Clinical Trial.
OPtimising Treatment for MIld Systolic hypertension in the Elderly (OPTiMISE): protocol for a randomised controlled non-inferiority trial.
Sheppard JP, Burt J, Lown M, Temple E, Benson J, Ford GA, Heneghan C, Hobbs FDR, Jowett S, Little P, Mant J, Mollison J, Nickless A, Ogburn E, Payne R, Williams M, Yu LM, McManus RJ. Sheppard JP, et al. Among authors: temple e. BMJ Open. 2018 Oct 4;8(9):e022930. doi: 10.1136/bmjopen-2018-022930. BMJ Open. 2018. PMID: 30287610 Free PMC article.
A randomised controlled trial of blood pressure self-monitoring in the management of hypertensive pregnancy. OPTIMUM-BP: A feasibility trial.
Pealing LM, Tucker KL, Mackillop LH, Crawford C, Wilson H, Nickless A, Temple E, Chappell LC, McManus RJ; OPTIMUM-BP Investigators. Pealing LM, et al. Among authors: temple e. Pregnancy Hypertens. 2019 Oct;18:141-149. doi: 10.1016/j.preghy.2019.09.018. Epub 2019 Oct 13. Pregnancy Hypertens. 2019. PMID: 31618706 Free article. Clinical Trial.
Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients With Hypertension Aged 80 Years and Older: The OPTIMISE Randomized Clinical Trial.
Sheppard JP, Burt J, Lown M, Temple E, Lowe R, Fraser R, Allen J, Ford GA, Heneghan C, Hobbs FDR, Jowett S, Kodabuckus S, Little P, Mant J, Mollison J, Payne RA, Williams M, Yu LM, McManus RJ; OPTIMISE Investigators. Sheppard JP, et al. Among authors: temple e. JAMA. 2020 May 26;323(20):2039-2051. doi: 10.1001/jama.2020.4871. JAMA. 2020. PMID: 32453368 Free PMC article. Clinical Trial.
Generalizability of Blood Pressure Lowering Trials to Older Patients: Cross-Sectional Analysis.
Sheppard JP, Lown M, Burt J, Temple E, Lowe R, Ashby H, Todd O, Allen J, Ford GA, Fraser R, Heneghan C, Hobbs FDR, Jowett S, Little P, Mant J, Mollison J, Payne R, Williams M, Yu LM, McManus RJ. Sheppard JP, et al. Among authors: temple e. J Am Geriatr Soc. 2020 Nov;68(11):2508-2515. doi: 10.1111/jgs.16749. Epub 2020 Sep 8. J Am Geriatr Soc. 2020. PMID: 32898307 Free article.
Clinical and cost-effectiveness of nurse-delivered sleep restriction therapy for insomnia in primary care (HABIT): a pragmatic, superiority, open-label, randomised controlled trial.
Kyle SD, Siriwardena AN, Espie CA, Yang Y, Petrou S, Ogburn E, Begum N, Maurer LF, Robinson B, Gardner C, Lee V, Armstrong S, Pattinson J, Mort S, Temple E, Harris V, Yu LM, Bower P, Aveyard P. Kyle SD, et al. Among authors: temple e. Lancet. 2023 Sep 16;402(10406):975-987. doi: 10.1016/S0140-6736(23)00683-9. Epub 2023 Aug 10. Lancet. 2023. PMID: 37573859 Free article. Clinical Trial.
Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course.
Schirmer M, Stražar M, Avila-Pacheco J, Rojas-Tapias DF, Brown EM, Temple E, Deik A, Bullock K, Jeanfavre S, Pierce K, Jin S, Invernizzi R, Pust MM, Costliow Z, Mack DR, Griffiths AM, Walters T, Boyle BM, Kugathasan S, Vlamakis H, Hyams J, Denson L, Clish CB, Xavier RJ. Schirmer M, et al. Among authors: temple e. Cell Host Microbe. 2024 Feb 14;32(2):209-226.e7. doi: 10.1016/j.chom.2023.12.013. Epub 2024 Jan 11. Cell Host Microbe. 2024. PMID: 38215740
66 results