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Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming.
Sun Z, Kwon JS, Ren Y, Chen S, Walker CK, Lu X, Cates K, Karahan H, Sviben S, Fitzpatrick JAJ, Valdez C, Houlden H, Karch CM, Bateman RJ, Sato C, Mennerick SJ, Diamond MI, Kim J, Tanzi RE, Holtzman DM, Yoo AS. Sun Z, et al. Among authors: diamond mi. Science. 2024 Aug 2;385(6708):adl2992. doi: 10.1126/science.adl2992. Epub 2024 Aug 2. Science. 2024. PMID: 39088624
Trans-cellular propagation of Tau aggregation by fibrillar species.
Kfoury N, Holmes BB, Jiang H, Holtzman DM, Diamond MI. Kfoury N, et al. Among authors: diamond mi. J Biol Chem. 2012 Jun 1;287(23):19440-51. doi: 10.1074/jbc.M112.346072. Epub 2012 Mar 29. J Biol Chem. 2012. PMID: 22461630 Free PMC article.
Proteopathic tau seeding predicts tauopathy in vivo.
Holmes BB, Furman JL, Mahan TE, Yamasaki TR, Mirbaha H, Eades WC, Belaygorod L, Cairns NJ, Holtzman DM, Diamond MI. Holmes BB, et al. Among authors: diamond mi. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):E4376-85. doi: 10.1073/pnas.1411649111. Epub 2014 Sep 26. Proc Natl Acad Sci U S A. 2014. PMID: 25261551 Free PMC article.
Anti-tau antibody reduces insoluble tau and decreases brain atrophy.
Yanamandra K, Jiang H, Mahan TE, Maloney SE, Wozniak DF, Diamond MI, Holtzman DM. Yanamandra K, et al. Among authors: diamond mi. Ann Clin Transl Neurol. 2015 Mar;2(3):278-88. doi: 10.1002/acn3.176. Epub 2015 Jan 23. Ann Clin Transl Neurol. 2015. PMID: 25815354 Free PMC article.
Endogenous recapitulation of Alzheimer's disease neuropathology through human 3D direct neuronal reprogramming.
Sun Z, Kwon JS, Ren Y, Chen S, Cates K, Lu X, Walker CK, Karahan H, Sviben S, Fitzpatrick JAJ, Valdez C, Houlden H, Karch CM, Bateman RJ, Sato C, Mennerick SJ, Diamond MI, Kim J, Tanzi RE, Holtzman DM, Yoo AS. Sun Z, et al. Among authors: diamond mi. bioRxiv [Preprint]. 2023 May 25:2023.05.24.542155. doi: 10.1101/2023.05.24.542155. bioRxiv. 2023. PMID: 37292658 Free PMC article. Preprint.
Prion-like mechanisms in neurodegenerative diseases.
Frost B, Diamond MI. Frost B, et al. Among authors: diamond mi. Nat Rev Neurosci. 2010 Mar;11(3):155-9. doi: 10.1038/nrn2786. Epub 2009 Dec 23. Nat Rev Neurosci. 2010. PMID: 20029438 Free PMC article. Review.
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.
DeVos SL, Miller RL, Schoch KM, Holmes BB, Kebodeaux CS, Wegener AJ, Chen G, Shen T, Tran H, Nichols B, Zanardi TA, Kordasiewicz HB, Swayze EE, Bennett CF, Diamond MI, Miller TM. DeVos SL, et al. Among authors: diamond mi. Sci Transl Med. 2017 Jan 25;9(374):eaag0481. doi: 10.1126/scitranslmed.aag0481. Sci Transl Med. 2017. PMID: 28123067 Free PMC article.
112 results