Handley TNG - Search Results

1

Enhancing the Intrinsic Antiplasmodial Activity and Improving the Stability and Selectivity of a Tunable Peptide Scaffold Derived from Human Platelet Factor 4.

Lawrence N, Handley TNG, de Veer SJ, Harding MD, Andraszek A, Hall L, Raven KD, Duffy S, Avery VM, Craik DJ, Malins LR, McMorran BJ. Lawrence N, et al. Among authors: handley tng. ACS Infect Dis. 2024 Aug 9;10(8):2899-2912. doi: 10.1021/acsinfecdis.4c00276. Epub 2024 Aug 1. ACS Infect Dis. 2024. PMID: 39087267 Free PMC article.

2

Scalable and Efficient In Planta Biosynthesis of Sunflower Trypsin Inhibitor-1 (SFTI) Peptide Therapeutics.

Handley TNG, Jackson MA, Craik DJ. Handley TNG, et al. Methods Mol Biol. 2022;2371:117-142. doi: 10.1007/978-1-0716-1689-5_7. Methods Mol Biol. 2022. PMID: 34596846

3

Cyclotide Structures Revealed by NMR, with a Little Help from X-ray Crystallography.

Handley TNG, Wang CK, Harvey PJ, Lawrence N, Craik DJ. Handley TNG, et al. Chembiochem. 2020 Dec 11;21(24):3463-3475. doi: 10.1002/cbic.202000315. Epub 2020 Oct 1. Chembiochem. 2020. PMID: 32656966 Review.

4

Cationic Antimicrobial Peptides Are Leading the Way to Combat Oropathogenic Infections.

Lin B, Li R, Handley TNG, Wade JD, Li W, O'Brien-Simpson NM. Lin B, et al. Among authors: handley tng. ACS Infect Dis. 2021 Nov 12;7(11):2959-2970. doi: 10.1021/acsinfecdis.1c00424. Epub 2021 Sep 30. ACS Infect Dis. 2021. PMID: 34587737

5

A Lipidated Single-B-Chain Derivative of Relaxin Exhibits Improved In Vitro Serum Stability without Altering Activity.

Praveen P, Wang C, Handley TNG, Wu H, Samuel CS, Bathgate RAD, Hossain MA. Praveen P, et al. Among authors: handley tng. Int J Mol Sci. 2023 Apr 1;24(7):6616. doi: 10.3390/ijms24076616. Int J Mol Sci. 2023. PMID: 37047588 Free PMC article.

6

Development of Novel High-Affinity Antagonists for the Relaxin Family Peptide Receptor 1.

Hossain MA, Praveen P, Noorzi NA, Wu H, Harrison IP, Handley T, Selemidis S, Samuel CS, Bathgate RAD. Hossain MA, et al. ACS Pharmacol Transl Sci. 2023 May 3;6(5):842-853. doi: 10.1021/acsptsci.3c00053. eCollection 2023 May 12. ACS Pharmacol Transl Sci. 2023. PMID: 37200817 Free PMC article.

7

Further Developments towards a Minimal Potent Derivative of Human Relaxin-2.

Handley TNG, Praveen P, Tailhades J, Wu H, Bathgate RAD, Hossain MA. Handley TNG, et al. Int J Mol Sci. 2023 Aug 11;24(16):12670. doi: 10.3390/ijms241612670. Int J Mol Sci. 2023. PMID: 37628851 Free PMC article.

8

Total Chemical Synthesis of Aggregation-Prone Disulfide-Rich Starfish Peptides.

Wu H, Praveen P, Handley TNG, Chandrashekar C, Cummins SF, Bathgate RAD, Hossain MA. Wu H, et al. Among authors: handley tng. Chemistry. 2024 Jun 12;30(33):e202400933. doi: 10.1002/chem.202400933. Epub 2024 May 15. Chemistry. 2024. PMID: 38609334

9

Developing insulin-like peptide 5-based antagonists for the G protein-coupled receptor, RXFP4.

Wu H, Handley TNG, Hoare BL, Hartono HA, Scott DJ, Chalmers DK, Bathgate RAD, Hossain MA. Wu H, et al. Among authors: handley tng. Biochem Pharmacol. 2024 Jun;224:116239. doi: 10.1016/j.bcp.2024.116239. Epub 2024 Apr 27. Biochem Pharmacol. 2024. PMID: 38679208

10

Development of a synthetic relaxin-3/INSL5 chimeric peptide ligand for NanoBiT complementation binding assays.

Wu H, Hoare BL, Handley TNG, Akhter Hossain M, Bathgate RAD. Wu H, et al. Among authors: handley tng. Biochem Pharmacol. 2024 Jun;224:116238. doi: 10.1016/j.bcp.2024.116238. Epub 2024 Apr 26. Biochem Pharmacol. 2024. PMID: 38677442

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