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Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis.
Wathieu C, Lavergne A, Xu X, Rolot M, Nemazanyy I, Shostak K, El Hachem N, Maurizy C, Leemans C, Close P, Nguyen L, Desmet C, Tielens S, Dewals BG, Chariot A. Wathieu C, et al. Among authors: nemazanyy i. EMBO J. 2024 Sep;43(18):3916-3947. doi: 10.1038/s44318-024-00184-4. Epub 2024 Jul 31. EMBO J. 2024. PMID: 39085648 Free PMC article.
Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization.
Chen D, Nemazanyy I, Peulen O, Shostak K, Xu X, Tang SC, Wathieu C, Turchetto S, Tielens S, Nguyen L, Close P, Desmet C, Klein S, Florin A, Büttner R, Petrellis G, Dewals B, Chariot A. Chen D, et al. Among authors: nemazanyy i. EMBO J. 2022 Sep 15;41(18):e109353. doi: 10.15252/embj.2021109353. Epub 2022 Aug 3. EMBO J. 2022. PMID: 35920020 Free PMC article.
The E3 ligase COP1 promotes ERα signaling and suppresses EMT in breast cancer.
Tang SC, Lion Q, Peulen O, Chariot P, Lavergne A, Mayer A, Fuster PA, Close P, Klein S, Florin A, Büttner R, Nemazanyy I, Shostak K, Chariot A. Tang SC, et al. Among authors: nemazanyy i. Oncogene. 2022 Jan;41(2):173-190. doi: 10.1038/s41388-021-02038-3. Epub 2021 Oct 29. Oncogene. 2022. PMID: 34716429
Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy.
Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M. Rashid T, et al. Among authors: nemazanyy i. EMBO J. 2019 Jan 3;38(1):e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov 12. EMBO J. 2019. PMID: 30420558 Free PMC article.
Expression of the monocarboxylate transporter MCT1 is required for virus-specific mouse CD8+ T cell memory development.
D'Aria S, Maquet C, Li S, Dhup S, Lepez A, Kohler A, Van Hée VF, Dadhich RK, Frenière M, Andris F, Nemazanyy I, Sonveaux P, Machiels B, Gillet L, Braun MY. D'Aria S, et al. Among authors: nemazanyy i. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2306763121. doi: 10.1073/pnas.2306763121. Epub 2024 Mar 18. Proc Natl Acad Sci U S A. 2024. PMID: 38498711 Free PMC article.
Regulatory T Cell Stability and Migration Are Dependent on mTOR.
Vallion R, Divoux J, Glauzy S, Ronin E, Lombardi Y, Lubrano di Ricco M, Grégoire S, Nemazanyy I, Durand A, Fradin D, Lucas B, Salomon BL. Vallion R, et al. Among authors: nemazanyy i. J Immunol. 2020 Oct 1;205(7):1799-1809. doi: 10.4049/jimmunol.1901480. Epub 2020 Aug 24. J Immunol. 2020. PMID: 32839235
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