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874 results

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Page 1
Structural Optimization of Oxaprozin for Selective Inverse Nurr1 Agonism.
Willems S, Busch R, Nawa F, Ballarotto M, Lillich FF, Kasch T, López-García Ú, Marschner JA, Rüger LA, Renelt B, Ohrndorf J, Arifi S, Zaienne D, Proschak E, Pabel J, Merk D. Willems S, et al. Among authors: busch r. J Med Chem. 2024 Aug 8;67(15):13324-13348. doi: 10.1021/acs.jmedchem.4c01218. Epub 2024 Jul 30. J Med Chem. 2024. PMID: 39081058
Development of a Potent Nurr1 Agonist Tool for In Vivo Applications.
Vietor J, Gege C, Stiller T, Busch R, Schallmayer E, Kohlhof H, Höfner G, Pabel J, Marschner JA, Merk D. Vietor J, et al. Among authors: busch r. J Med Chem. 2023 May 11;66(9):6391-6402. doi: 10.1021/acs.jmedchem.3c00415. Epub 2023 Apr 26. J Med Chem. 2023. PMID: 37127285 Free PMC article.
Nurr1 Modulation Mediates Neuroprotective Effects of Statins.
Willems S, Marschner JA, Kilu W, Faudone G, Busch R, Duensing-Kropp S, Heering J, Merk D. Willems S, et al. Among authors: busch r. Adv Sci (Weinh). 2022 Jun;9(18):e2104640. doi: 10.1002/advs.202104640. Epub 2022 Apr 30. Adv Sci (Weinh). 2022. PMID: 35488520 Free PMC article.
Chemogenomics for NR1 nuclear hormone receptors.
Isigkeit L, Schallmayer E, Busch R, Brunello L, Menge A, Elson L, Müller S, Knapp S, Stolz A, Marschner JA, Merk D. Isigkeit L, et al. Among authors: busch r. Nat Commun. 2024 Jun 18;15(1):5201. doi: 10.1038/s41467-024-49493-6. Nat Commun. 2024. PMID: 38890295 Free PMC article.
Association of Hypertension With Early-Onset Cryptogenic Ischemic Stroke by the Presence of Patent Foramen Ovale: A Case-Control Study.
Putaala J, von Sarnowski B, Schminke U, Busch R, Martinez-Majander N, Ylikotila P, Lautamäki R, Zedde M, Grimaldi T, Sarkanen T, Virtanen M, Ryliskiene K, Zakarkaite D, Tulkki L, Pirinen J, Licenik R, Ferdinand P, Oxley C, Kõrv J, Muda P, Pezzini A, Lombardi CM, Tsivgoulis G, Suihko S, Tolppanen H, Fonseca AC, Martínez-Sánchez P, Amaya Pascasio L, Yesilot N, Elitok A, Waje-Andreassen U, Saeed S, Redfors P, Bech-Hanssen O, Huhtakangas J, Hedman M, Jäkälä P, Sinisalo J, Gerdts E; SECRETO Study Group. Putaala J, et al. Among authors: busch r. J Am Heart Assoc. 2024 Nov 5;13(21):e036254. doi: 10.1161/JAHA.124.036254. Epub 2024 Oct 25. J Am Heart Assoc. 2024. PMID: 39450719 Free article. No abstract available.
Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial.
Deanfield J, Verma S, Scirica BM, Kahn SE, Emerson SS, Ryan D, Lingvay I, Colhoun HM, Plutzky J, Kosiborod MN, Hovingh GK, Hardt-Lindberg S, Frenkel O, Weeke PE, Rasmussen S, Goudev A, Lang CC, Urina-Triana M, Pietilä M, Lincoff AM; SELECT Trial Investigators. Deanfield J, et al. Lancet. 2024 Aug 24;404(10454):773-786. doi: 10.1016/S0140-6736(24)01498-3. Lancet. 2024. PMID: 39181597 Free article. Clinical Trial.
874 results