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Exploring a unique class of flavoenzymes: Identification and biochemical characterization of ribosomal RNA dihydrouridine synthase.
Toubdji S, Thullier Q, Kilz LM, Marchand V, Yuan Y, Sudol C, Goyenvalle C, Jean-Jean O, Rose S, Douthwaite S, Hardy L, Baharoglu Z, de Crécy-Lagard V, Helm M, Motorin Y, Hamdane D, Brégeon D. Toubdji S, et al. Among authors: hamdane d. Proc Natl Acad Sci U S A. 2024 Aug 6;121(32):e2401981121. doi: 10.1073/pnas.2401981121. Epub 2024 Jul 30. Proc Natl Acad Sci U S A. 2024. PMID: 39078675
Functional redundancy in tRNA dihydrouridylation.
Sudol C, Kilz LM, Marchand V, Thullier Q, Guérineau V, Goyenvalle C, Faivre B, Toubdji S, Lombard M, Jean-Jean O, de Crécy-Lagard V, Helm M, Motorin Y, Brégeon D, Hamdane D. Sudol C, et al. Among authors: hamdane d. Nucleic Acids Res. 2024 Jun 10;52(10):5880-5894. doi: 10.1093/nar/gkae325. Nucleic Acids Res. 2024. PMID: 38682613 Free PMC article.
Dihydrouridine synthesis in tRNAs is under reductive evolution in Mollicutes.
Faivre B, Lombard M, Fakroun S, Vo CD, Goyenvalle C, Guérineau V, Pecqueur L, Fontecave M, De Crécy-Lagard V, Brégeon D, Hamdane D. Faivre B, et al. Among authors: hamdane d. RNA Biol. 2021 Dec;18(12):2278-2289. doi: 10.1080/15476286.2021.1899653. Epub 2021 Mar 22. RNA Biol. 2021. PMID: 33685366 Free PMC article.
An extended dsRBD is required for post-transcriptional modification in human tRNAs.
Bou-Nader C, Pecqueur L, Bregeon D, Kamah A, Guérineau V, Golinelli-Pimpaneau B, Guimarães BG, Fontecave M, Hamdane D. Bou-Nader C, et al. Among authors: hamdane d. Nucleic Acids Res. 2015 Oct 30;43(19):9446-56. doi: 10.1093/nar/gkv989. Epub 2015 Oct 1. Nucleic Acids Res. 2015. PMID: 26429968 Free PMC article.
56 results