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14 results

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Page 1
Prognostic impact of quantitative flow ratio (QFR)-consistent complete revascularization in patients with myocardial infarction and multivessel coronary artery disease.
Erbay A, Penzel L, Abdelwahed YS, Heuberger A, Schatz AS, Seppelt C, Schlender LS, Steiner J, Haghikia A, Steven S, Landmesser U, Stähli BE, Leistner DM. Erbay A, et al. Among authors: seppelt c. Am Heart J. 2024 Oct;276:22-30. doi: 10.1016/j.ahj.2024.07.011. Epub 2024 Jul 20. Am Heart J. 2024. PMID: 39033995 Free article. Clinical Trial.
Cholesterol crystals at the culprit lesion in patients with acute coronary syndrome are associated with worse cardiovascular outcomes at two years follow up - results from the translational OPTICO-ACS study program.
Nelles G, Abdelwahed YS, Seppelt C, Meteva D, Stähli BE, Rai H, Seegers LM, Sieronski L, Musfeldt J, Gerhardt T, Riedel M, Skurk C, Haghikia A, Sinning D, Dreger H, Knebel F, Trippel TD, Krisper M, Klotsche J, Joner M, Landmesser U, Leistner DM. Nelles G, et al. Among authors: seppelt c. Int J Cardiol. 2024 Mar 15;399:131665. doi: 10.1016/j.ijcard.2023.131665. Epub 2023 Dec 22. Int J Cardiol. 2024. PMID: 38141724
Spotty calcium deposits within acute coronary syndrome (ACS)-causing culprit lesions impact inflammatory vessel-wall interactions and are associated with higher cardiovascular event rates at one year follow-up: Results from the prospective translational OPTICO-ACS study program.
Nelles G, Abdelwahed YS, Alyaqoob A, Seppelt C, Stähli BE, Meteva D, Kränkel N, Haghikia A, Skurk C, Dreger H, Knebel F, Trippel TD, Krisper M, Sieronski L, Gerhardt T, Zanders L, Klotsche J, Landmesser U, Joner M, Leistner DM. Nelles G, et al. Among authors: seppelt c. Atherosclerosis. 2023 Nov;385:117284. doi: 10.1016/j.atherosclerosis.2023.117284. Epub 2023 Sep 15. Atherosclerosis. 2023. PMID: 37871405
Coronary microevaginations characterize culprit plaques and their inflammatory microenvironment in a subtype of acute coronary syndrome with intact fibrous cap: results from the prospective translational OPTICO-ACS study.
Seppelt C, Abdelwahed YS, Meteva D, Nelles G, Stähli BE, Erbay A, Kränkel N, Sieronski L, Skurk C, Haghikia A, Sinning D, Dreger H, Knebel F, Trippel TD, Krisper M, Gerhardt T, Rai H, Klotsche J, Joner M, Landmesser U, Leistner DM. Seppelt C, et al. Eur Heart J Cardiovasc Imaging. 2024 Jan 29;25(2):175-184. doi: 10.1093/ehjci/jead154. Eur Heart J Cardiovasc Imaging. 2024. PMID: 37395586
Cardiovascular disease biomarkers derived from circulating cell-free DNA methylation.
Cuadrat RRC, Kratzer A, Arnal HG, Rathgeber AC, Wreczycka K, Blume A, Gündüz IB, Ebenal V, Mauno T, Osberg B, Moobed M, Hartung J, Jakobs K, Seppelt C, Meteva D, Haghikia A, Leistner DM, Landmesser U, Akalin A. Cuadrat RRC, et al. Among authors: seppelt c. NAR Genom Bioinform. 2023 Jun 28;5(2):lqad061. doi: 10.1093/nargab/lqad061. eCollection 2023 Jun. NAR Genom Bioinform. 2023. PMID: 37388821 Free PMC article.
Culprit plaque morphology determines inflammatory risk and clinical outcomes in acute coronary syndrome.
Gerhardt T, Seppelt C, Abdelwahed YS, Meteva D, Wolfram C, Stapmanns P, Erbay A, Zanders L, Nelles G, Musfeld J, Sieronski L, Stähli BE, Montone RA, Vergallo R, Haghikia A, Skurk C, Knebel F, Dreger H, Trippel TD, Rai H, Joner M, Klotsche J, Libby P, Crea F, Kränkel N, Landmesser U, Leistner DM; OPTICO-ACS study group. Gerhardt T, et al. Among authors: seppelt c. Eur Heart J. 2023 Oct 12;44(38):3911-3925. doi: 10.1093/eurheartj/ehad334. Eur Heart J. 2023. PMID: 37381774
Toll-like receptor 2, hyaluronan, and neutrophils play a key role in plaque erosion: the OPTICO-ACS study.
Meteva D, Vinci R, Seppelt C, Abdelwahed YS, Pedicino D, Nelles G, Skurk C, Haghikia A, Rauch-Kröhnert U, Gerhardt T, Straessler E, Zhao Y, Golla F, Joner M, Rai H, Kratzer A, Arnal HG, Liuzzo G, Klotsche J, Crea F, Landmesser U, Leistner DM, Kränkel N. Meteva D, et al. Among authors: seppelt c. Eur Heart J. 2023 Oct 12;44(38):3892-3907. doi: 10.1093/eurheartj/ehad379. Eur Heart J. 2023. PMID: 37381760
Rapid Inflammasome Activation Is Attenuated in Post-Myocardial Infarction Monocytes.
Giral H, Franke V, Moobed M, Müller MF, Lübking L, James DM, Hartung J, Kuschnerus K, Meteva D, Seppelt C, Jakob P, Klingenberg R, Kränkel N, Leistner D, Zeller T, Blankenberg S, Zimmermann F, Haghikia A, Lüscher TF, Akalin A, Landmesser U, Kratzer A. Giral H, et al. Among authors: seppelt c. Front Immunol. 2022 Apr 26;13:857455. doi: 10.3389/fimmu.2022.857455. eCollection 2022. Front Immunol. 2022. PMID: 35558073 Free PMC article.
Coexistence of calcified- and lipid-containing plaque components and their association with incidental rupture points in acute coronary syndrome-causing culprit lesions: results from the prospective OPTICO-ACS study.
Abdelwahed YS, Nelles G, Frick C, Seppelt C, Meteva D, Stähli BE, Rai H, Riedel M, Skurk C, Rauch-Kröhnert U, Haghikia A, Sinning D, Dreger H, Knebel F, Trippel T, Krisper M, Klotsche J, Joner M, Landmesser U, Leistner DM. Abdelwahed YS, et al. Among authors: seppelt c. Eur Heart J Cardiovasc Imaging. 2022 Nov 17;23(12):1598-1605. doi: 10.1093/ehjci/jeab247. Eur Heart J Cardiovasc Imaging. 2022. PMID: 34904655
14 results