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Page 1
Global siRNA Screen Reveals Critical Human Host Factors of SARS-CoV-2 Multicycle Replication.
Yin X, Pu Y, Yuan S, Pache L, Churas C, Weston S, Riva L, Simons LM, Cisneros WJ, Clausen T, De Jesus PD, Kim HN, Fuentes D, Whitelock J, Esko J, Lord M, Mena I, García-Sastre A, Hultquist JF, Frieman MB, Ideker T, Pratt D, Martin-Sancho L, Chanda SK. Yin X, et al. bioRxiv [Preprint]. 2024 Jul 10:2024.07.10.602835. doi: 10.1101/2024.07.10.602835. bioRxiv. 2024. PMID: 39026801 Free PMC article. Preprint.
Prophylactic protection against respiratory viruses conferred by a prototype live attenuated influenza virus vaccine.
Rathnasinghe R, Salvatore M, Zheng H, Jangra S, Kehrer T, Mena I, Schotsaert M, Muster T, Palese P, García-Sastre A. Rathnasinghe R, et al. bioRxiv [Preprint]. 2021 Apr 28:2021.04.28.441797. doi: 10.1101/2021.04.28.441797. bioRxiv. 2021. Update in: Sci Rep. 2021 Nov 12;11(1):22164. doi: 10.1038/s41598-021-01780-8. PMID: 33948589 Free PMC article. Updated. Preprint.
Trivalent NDV-HXP-S vaccine protects against phylogenetically distant SARS-CoV-2 variants of concern in mice.
González-Domínguez I, Martínez JL, Slamanig S, Lemus N, Liu Y, Lai TY, Carreño JM, Singh A G, Singh B G, Schotsaert M, Mena I, McCroskery S, Coughlan L, Krammer F, García-Sastre A, Palese P, Sun W. González-Domínguez I, et al. bioRxiv [Preprint]. 2022 Mar 22:2022.03.21.485247. doi: 10.1101/2022.03.21.485247. bioRxiv. 2022. Update in: Microbiol Spectr. 2022 Jun 29;10(3):e0153822. doi: 10.1128/spectrum.01538-22. PMID: 35350201 Free PMC article. Updated. Preprint.
Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants.
Muñoz-Alía MÁ, Nace RA, Balakrishnan B, Zhang L, Packiriswamy N, Singh G, Warang P, Mena I, Narjari R, Vandergaast R, García-Sastre A, Schotsaert M, Russell SJ. Muñoz-Alía MÁ, et al. bioRxiv [Preprint]. 2022 Dec 16:2022.12.16.520799. doi: 10.1101/2022.12.16.520799. bioRxiv. 2022. Update in: mBio. 2024 Feb 14;15(2):e0292823. doi: 10.1128/mbio.02928-23. PMID: 36561187 Free PMC article. Updated. Preprint.
Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters.
García-Bernalt Diego J, Singh G, Jangra S, Handrejk K, Laporte M, Chang LA, El Zahed SS, Pache L, Chang MW, Warang P, Aslam S, Mena I, Webb BT, Benner C, García-Sastre A, Schotsaert M. García-Bernalt Diego J, et al. bioRxiv [Preprint]. 2023 May 23:2023.05.22.541294. doi: 10.1101/2023.05.22.541294. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Jan 10;20(1):e1011805. doi: 10.1371/journal.ppat.1011805. PMID: 37425792 Free PMC article. Updated. Preprint.
Generation of antigen-specific memory CD4 T cells by heterologous immunization enhances the magnitude of the germinal center response upon influenza infection.
Sircy LM, Ramstead AG, Joshi H, Baessler A, Mena I, García-Sastre A, Williams MA, Scott Hale J. Sircy LM, et al. bioRxiv [Preprint]. 2023 Aug 31:2023.08.29.555253. doi: 10.1101/2023.08.29.555253. bioRxiv. 2023. Update in: PLoS Pathog. 2024 Sep 16;20(9):e1011639. doi: 10.1371/journal.ppat.1011639. PMID: 37693425 Free PMC article. Updated. Preprint.
Inhibition of SARS-CoV-2 growth in the lungs of mice by a peptide-conjugated morpholino oligomer targeting viral RNA.
Sakai A, Singh G, Khoshbakht M, Bittner S, Löhr CV, Diaz-Tapia R, Warang P, White K, Luo LL, Tolbert B, Blanco M, Chow A, Guttman M, Li C, Bao Y, Ho J, Maurer-Stroh S, Chatterjee A, Chanda S, García-Sastre A, Schotsaert M, Teijaro JR, Moulton HM, Stein DA. Sakai A, et al. Mol Ther Nucleic Acids. 2024 Sep 10;35(4):102331. doi: 10.1016/j.omtn.2024.102331. eCollection 2024 Dec 10. Mol Ther Nucleic Acids. 2024. PMID: 39376996 Free PMC article.
Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant.
Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Ummadi M, Rojc A, Turner J, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hosmillo M, Hiatt J, Jahun A, Goodfellow IG, Fabius JM, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Swaney DL, Garcia-Sastre A, Jolly C, Towers GJ, Krogan NJ. Thorne LG, et al. bioRxiv [Preprint]. 2021 Jun 7:2021.06.06.446826. doi: 10.1101/2021.06.06.446826. bioRxiv. 2021. Update in: Nature. 2022 Feb;602(7897):487-495. doi: 10.1038/s41586-021-04352-y. PMID: 34127972 Free PMC article. Updated. Preprint.
Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer.
Cool K, Gaudreault NN, Morozov I, Trujillo JD, Meekins DA, McDowell C, Carossino M, Bold D, Kwon T, Balaraman V, Madden DW, Artiaga BL, Pogranichniy RM, Sosa GR, Henningson J, Wilson WC, Balasuriya UBR, García-Sastre A, Richt JA. Cool K, et al. bioRxiv [Preprint]. 2021 Aug 24:2021.08.15.456341. doi: 10.1101/2021.08.15.456341. bioRxiv. 2021. Update in: Emerg Microbes Infect. 2022 Dec;11(1):95-112. doi: 10.1080/22221751.2021.2012528. PMID: 34426811 Free PMC article. Updated. Preprint.
Unambiguous detection of SARS-CoV-2 subgenomic mRNAs with single cell RNA sequencing.
Cohen P, DeGrace EJ, Danziger O, Patel RS, Barrall EA, Bobrowski T, Kehrer T, Cupic A, Miorin L, García-Sastre A, Rosenberg BR. Cohen P, et al. bioRxiv [Preprint]. 2023 Feb 23:2021.11.22.469642. doi: 10.1101/2021.11.22.469642. bioRxiv. 2023. Update in: Microbiol Spectr. 2023 Sep 7:e0077623. doi: 10.1128/spectrum.00776-23. PMID: 34845443 Free PMC article. Updated. Preprint.
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