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Page 1
Pediatric T-cell lymphoblastic lymphomas but not leukemias harbor TRB::NOTCH1 fusions with unfavorable outcome.
Te Vrugt M, Wessolowski J, Randau G, Alfert A, Mueller S, Scholten K, Sopalla C, Lanvers-Kaminsky C, Hotfilder M, Lamp F, Damm-Welk C, Luedersen J, Escherich G, Zur Stadt U, Behrmann L, Woessmann W, Oschlies I, Marzi M, Zimmermann M, Burkhardt B. Te Vrugt M, et al. Among authors: hotfilder m. Blood. 2024 Sep 26;144(13):1412-1417. doi: 10.1182/blood.2024025307. Blood. 2024. PMID: 39024510
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.
le Viseur C, Hotfilder M, Bomken S, Wilson K, Röttgers S, Schrauder A, Rosemann A, Irving J, Stam RW, Shultz LD, Harbott J, Jürgens H, Schrappe M, Pieters R, Vormoor J. le Viseur C, et al. Among authors: hotfilder m. Cancer Cell. 2008 Jul 8;14(1):47-58. doi: 10.1016/j.ccr.2008.05.015. Cancer Cell. 2008. PMID: 18598943 Free PMC article.
Lack of expression of the chondroitin sulphate proteoglycan neuron-glial antigen 2 on candidate stem cell populations in paediatric acute myeloid leukaemia/abn(11q23) and acute lymphoblastic leukaemia/t(4;11).
Neudenberger J, Hotfilder M, Rosemann A, Langebrake C, Reinhardt D, Pieters R, Schrauder A, Schrappe M, Röttgers S, Harbott J, Vormoor J. Neudenberger J, et al. Among authors: hotfilder m. Br J Haematol. 2006 May;133(3):337-44. doi: 10.1111/j.1365-2141.2006.06013.x. Br J Haematol. 2006. PMID: 16643437 Free article.
The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting.
Kailayangiri S, Altvater B, Meltzer J, Pscherer S, Luecke A, Dierkes C, Titze U, Leuchte K, Landmeier S, Hotfilder M, Dirksen U, Hardes J, Gosheger G, Juergens H, Rossig C. Kailayangiri S, et al. Among authors: hotfilder m. Br J Cancer. 2012 Mar 13;106(6):1123-33. doi: 10.1038/bjc.2012.57. Epub 2012 Feb 28. Br J Cancer. 2012. PMID: 22374462 Free PMC article.
Group-specific cellular metabolism in Medulloblastoma.
Funke VLE, Walter C, Melcher V, Wei L, Sandmann S, Hotfilder M, Varghese J, Jäger N, Kool M, Jones DTW, Pfister SM, Milde T, Mynarek M, Rutkowski S, Seggewiss J, Jeising D, de Faria FW, Marquardt T, Albert TK, Schüller U, Kerl K. Funke VLE, et al. Among authors: hotfilder m. J Transl Med. 2023 Jun 5;21(1):363. doi: 10.1186/s12967-023-04211-6. J Transl Med. 2023. PMID: 37277823 Free PMC article.
S100A2 induces metastasis in non-small cell lung cancer.
Bulk E, Sargin B, Krug U, Hascher A, Jun Y, Knop M, Kerkhoff C, Gerke V, Liersch R, Mesters RM, Hotfilder M, Marra A, Koschmieder S, Dugas M, Berdel WE, Serve H, Müller-Tidow C. Bulk E, et al. Among authors: hotfilder m. Clin Cancer Res. 2009 Jan 1;15(1):22-9. doi: 10.1158/1078-0432.CCR-08-0953. Clin Cancer Res. 2009. PMID: 19118029
39 results