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Page 1
A clinically compatible in vitro drug-screening platform identifies therapeutic vulnerabilities in primary cultures of brain metastases.
Jeising S, Nickel AC, Trübel J, Felsberg J, Picard D, Leprivier G, Wolter M, Huynh MK, Olivera MB, Kaulich K, Häberle L, Esposito I, Klau GW, Steinmann J, Beez T, Rapp M, Sabel M, Dietrich S, Remke M, Cornelius JF, Reifenberger G, Qin N. Jeising S, et al. Among authors: nickel ac. J Neurooncol. 2024 Sep;169(3):613-623. doi: 10.1007/s11060-024-04763-7. Epub 2024 Jul 10. J Neurooncol. 2024. PMID: 38985431 Free PMC article.
Longitudinal stability of molecular alterations and drug response profiles in tumor spheroid cell lines enables reproducible analyses.
Nickel AC, Picard D, Qin N, Wolter M, Kaulich K, Hewera M, Pauck D, Marquardt V, Torga G, Muhammad S, Zhang W, Schnell O, Steiger HJ, Hänggi D, Fritsche E, Her NG, Nam DH, Carro MS, Remke M, Reifenberger G, Kahlert UD. Nickel AC, et al. Biomed Pharmacother. 2021 Dec;144:112278. doi: 10.1016/j.biopha.2021.112278. Epub 2021 Oct 7. Biomed Pharmacother. 2021. PMID: 34628166 Free article.
In-Vitro Use of Verteporfin for Photodynamic Therapy in Glioblastoma.
Jeising S, Geerling G, Guthoff R, Hänggi D, Sabel M, Rapp M, Nickel AC. Jeising S, et al. Among authors: nickel ac. Photodiagnosis Photodyn Ther. 2022 Dec;40:103049. doi: 10.1016/j.pdpdt.2022.103049. Epub 2022 Aug 4. Photodiagnosis Photodyn Ther. 2022. PMID: 35932958 Free article.
The development of a hiPSC-based platform to identify tissue-dependencies of IDH1 R132H.
Mehjardi NZ, Kessler J, Sanin AY, Picard D, Westhoff P, Nickel AC, Uhlmann C, Shi W, Steiger HJ, Remke M, Fischer I, Vordermark D, Croner RS, Kahlert UD. Mehjardi NZ, et al. Among authors: nickel ac. Cell Death Discov. 2023 Dec 12;9(1):452. doi: 10.1038/s41420-023-01747-w. Cell Death Discov. 2023. PMID: 38086797 Free PMC article.
Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide.
Vargas-Toscano A, Nickel AC, Li G, Kamp MA, Muhammad S, Leprivier G, Fritsche E, Barker RA, Sabel M, Steiger HJ, Zhang W, Hänggi D, Kahlert UD. Vargas-Toscano A, et al. Among authors: nickel ac. Cancers (Basel). 2020 Dec 21;12(12):3859. doi: 10.3390/cancers12123859. Cancers (Basel). 2020. PMID: 33371210 Free PMC article.
Progenitor cells derived from gene-engineered human induced pluripotent stem cells as synthetic cancer cell alternatives for in vitro pharmacology.
Uhlmann C, Nickel AC, Picard D, Rossi A, Li G, Hildebrandt B, Brockerhoff G, Bendt F, Hübenthal U, Hewera M, Steiger HJ, Wieczorek D, Perrakis A, Zhang W, Remke M, Koch K, Tigges J, Croner RS, Fritsche E, Kahlert UD. Uhlmann C, et al. Among authors: nickel ac. Biotechnol J. 2022 Jun;17(6):e2100693. doi: 10.1002/biot.202100693. Epub 2022 Apr 3. Biotechnol J. 2022. PMID: 35334498
A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity.
Koch K, Hartmann R, Tsiampali J, Uhlmann C, Nickel AC, He X, Kamp MA, Sabel M, Barker RA, Steiger HJ, Hänggi D, Willbold D, Maciaczyk J, Kahlert UD. Koch K, et al. Among authors: nickel ac. Cell Death Discov. 2020 Apr 16;6:20. doi: 10.1038/s41420-020-0258-3. eCollection 2020. Cell Death Discov. 2020. PMID: 32337072 Free PMC article.
37 results