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Page 1
A fibroblast-dependent TGF-β1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis.
Cohen ML, Brumwell AN, Ho TC, Garakani K, Montas G, Leong D, Ding VW, Golden JA, Trinh BN, Jablons DM, Matthay MA, Jones KD, Wolters PJ, Wei Y, Chapman HA, Le Saux CJ. Cohen ML, et al. Among authors: montas g. J Clin Invest. 2024 Jul 9;134(18):e174598. doi: 10.1172/JCI174598. J Clin Invest. 2024. PMID: 38980870 Free PMC article. Clinical Trial.
A fibroblast-dependent TGFβ1/sFRP2 noncanonical Wnt signaling axis underlies epithelial metaplasia in idiopathic pulmonary fibrosis.
Cohen ML, Brumwell AN, Che Ho T, Montas G, Golden JA, Jones KD, Wolters PJ, Wei Y, Chapman HA, Le Saux CJ. Cohen ML, et al. Among authors: montas g. bioRxiv [Preprint]. 2023 Aug 4:2023.08.02.551383. doi: 10.1101/2023.08.02.551383. bioRxiv. 2023. Update in: J Clin Invest. 2024 Jul 9;134(18):e174598. doi: 10.1172/JCI174598. PMID: 37577522 Free PMC article. Updated. Preprint.
Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis.
Chapman HA, Wei Y, Montas G, Leong D, Golden JA, Trinh BN, Wolters PJ, Le Saux CJ, Jones KD, Hills NK, Foster E, Oldham JM, Linderholm AL, Kotak P, Decaris M, Turner S, Song JW. Chapman HA, et al. Among authors: montas g. N Engl J Med. 2020 Mar 12;382(11):1068-1070. doi: 10.1056/NEJMc1915189. N Engl J Med. 2020. PMID: 32160670 Free PMC article. No abstract available.
Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study.
Solomon JJ, Danoff SK, Woodhead FA, Hurwitz S, Maurer R, Glaspole I, Dellaripa PF, Gooptu B, Vassallo R, Cox PG, Flaherty KR, Adamali HI, Gibbons MA, Troy L, Forrest IA, Lasky JA, Spencer LG, Golden J, Scholand MB, Chaudhuri N, Perrella MA, Lynch DA, Chambers DC, Kolb M, Spino C, Raghu G, Goldberg HJ, Rosas IO; TRAIL1 Network Investigators. Solomon JJ, et al. Lancet Respir Med. 2023 Jan;11(1):87-96. doi: 10.1016/S2213-2600(22)00260-0. Epub 2022 Sep 5. Lancet Respir Med. 2023. PMID: 36075242 Clinical Trial.