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A Phase II, Open-Label, Randomized Trial of Durvalumab With Olaparib or Cediranib in Patients With Mismatch Repair-Proficient Colorectal or Pancreatic Cancer.
Hernando-Calvo A, Han M, Ayodele O, Wang BX, Bruce JP, Abbas-Aghababazadeh F, Vila-Casadesús M, Sanz-Garcia E, Yang SYC, Berman HK, Vivancos A, Lam B, Lungu I, Salawu A, Stayner LA, Haibe-Kains B, Bedard PL, Avery L, Razak ARA, Pugh TJ, Spreafico A, Siu LL, Hansen AR. Hernando-Calvo A, et al. Among authors: hansen ar. Clin Colorectal Cancer. 2024 Sep;23(3):272-284.e9. doi: 10.1016/j.clcc.2024.05.002. Epub 2024 May 15. Clin Colorectal Cancer. 2024. PMID: 38960798 Free article. Clinical Trial.
Tumour heterogeneity in the clinic.
Bedard PL, Hansen AR, Ratain MJ, Siu LL. Bedard PL, et al. Among authors: hansen ar. Nature. 2013 Sep 19;501(7467):355-64. doi: 10.1038/nature12627. Nature. 2013. PMID: 24048068 Free PMC article.
Phase 1 trial design: is 3 + 3 the best?
Hansen AR, Graham DM, Pond GR, Siu LL. Hansen AR, et al. Cancer Control. 2014 Jul;21(3):200-8. doi: 10.1177/107327481402100304. Cancer Control. 2014. PMID: 24955703 Free article. Review.
Early phase clinical trials to identify optimal dosing and safety.
Cook N, Hansen AR, Siu LL, Abdul Razak AR. Cook N, et al. Among authors: hansen ar. Mol Oncol. 2015 May;9(5):997-1007. doi: 10.1016/j.molonc.2014.07.025. Epub 2014 Aug 14. Mol Oncol. 2015. PMID: 25160636 Free PMC article. Review.
281 results