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Page 1
Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Qiao M, Vardarajan BN, Cosacak MI, Kizil C, Jean-Francois M, Cuccaro M, Reyes-Dumeyer D, Cantwell L, Kuzma A, Vance JM, Gao S, Hendrie HC, Baiyewu O, Ogunniyi A, Akinyemi RO; Alzheimer's Disease Genetics Consortium; Lee WP, Martin ER, Wang LS, Beecham GW, Bush WS, Xu W, Jin F, Wang L, Farrer LA, Haines JL, Byrd GS, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C. Ray NR, et al. Among authors: byrd gs. Alzheimers Dement. 2024 Aug;20(8):5247-5261. doi: 10.1002/alz.13880. Epub 2024 Jul 3. Alzheimers Dement. 2024. PMID: 38958117 Free PMC article.
Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Logue MW, Schu M, Vardarajan BN, Farrell J, Bennett DA, Buxbaum JD, Byrd GS, Ertekin-Taner N, Evans D, Foroud T, Goate A, Graff-Radford NR, Kamboh MI, Kukull WA, Manly JJ; Alzheimer Disease Genetics Consortium; Alzheimer Disease Genetics Consortium. Logue MW, et al. Among authors: byrd gs. Alzheimers Dement. 2014 Nov;10(6):609-618.e11. doi: 10.1016/j.jalz.2014.06.010. Epub 2014 Aug 27. Alzheimers Dement. 2014. PMID: 25172201 Free PMC article.
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue MW, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hardy J, Hendrie HC, Hall KS, Goate AM, Lang R, Byrd GS, Kukull WA, Foroud TM, Farrer LA, Martin ER, Pericak-Vance MA, Schellenberg GD, Mayeux R, Haines JL, Thornton-Wells TA; Alzheimer Disease Genetics Consortium. Hohman TJ, et al. Among authors: byrd gs. Alzheimers Dement. 2016 Mar;12(3):233-43. doi: 10.1016/j.jalz.2015.02.012. Epub 2015 Jun 16. Alzheimers Dement. 2016. PMID: 26092349 Free PMC article.
Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ; Alzheimer's Disease Genetics Consortium; Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Farrer LA. Mez J, et al. Among authors: byrd gs. Alzheimers Dement. 2017 Feb;13(2):119-129. doi: 10.1016/j.jalz.2016.09.002. Epub 2016 Oct 20. Alzheimers Dement. 2017. PMID: 27770636 Free PMC article.
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JSK, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR; Alzheimer's Disease Genetics Consortium; Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. Jun GR, et al. Among authors: byrd gs. Alzheimers Dement. 2017 Jul;13(7):727-738. doi: 10.1016/j.jalz.2016.12.012. Epub 2017 Feb 7. Alzheimers Dement. 2017. PMID: 28183528 Free PMC article.
Immune and Inflammatory Pathways Implicated by Whole Blood Transcriptomic Analysis in a Diverse Ancestry Alzheimer's Disease Cohort.
Griswold AJ, Sivasankaran SK, Van Booven D, Gardner OK, Rajabli F, Whitehead PL, Hamilton-Nelson KL, Adams LD, Scott AM, Hofmann NK, Vance JM, Cuccaro ML, Bush WS, Martin ER, Byrd GS, Haines JL, Pericak-Vance MA, Beecham GW. Griswold AJ, et al. Among authors: byrd gs. J Alzheimers Dis. 2020;76(3):1047-1060. doi: 10.3233/JAD-190855. J Alzheimers Dis. 2020. PMID: 32597797
Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans.
Rajabli F, Tosto G, Hamilton-Nelson KL, Kunkle BW, Vardarajan BN, Naj A, Whitehead PG, Gardner OK, Bush WS, Sariya S, Mayeux RP, Farrer LA, Cuccaro ML, Vance JM, Griswold AJ, Schellenberg GD, Haines JL, Byrd GS, Reitz C, Beecham GW, Pericak-Vance MA, Martin ER; Alzheimer's Disease Genetics Consortium (ADGC), Collaboration on Alzheimer's Disease Research (CADRE) and Alzheimer's Disease Sequencing Project (ADSP). Rajabli F, et al. Among authors: byrd gs. Alzheimers Dement. 2023 Jun;19(6):2538-2548. doi: 10.1002/alz.12865. Epub 2022 Dec 20. Alzheimers Dement. 2023. PMID: 36539198 Free PMC article.
Leveraging African American family connectors for Alzheimer's disease genomic studies.
Byfield G, Starks TD, Luther R, Edwards CL, Lloyd SL, Caban-Holt A, Adams LD, Vance JM, Cuccaro M, Haines JL, Reitz C, Pericak-Vance MA, Byrd GS. Byfield G, et al. Among authors: byrd gs. Alzheimers Dement. 2023 Dec;19(12):5437-5446. doi: 10.1002/alz.13106. Epub 2023 May 22. Alzheimers Dement. 2023. PMID: 37212603
Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease.
Xicota L, Cosentino S, Vardarajan B, Mayeux R, Perls TT, Andersen SL, Zmuda JM, Thyagarajan B, Yashin A, Wojczynski MK, Krinsky-McHale S, Handen BL, Christian BT, Head E, Mapstone ME, Schupf N, Lee JH, Barral S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS). Xicota L, et al. Alzheimers Dement. 2024 Apr;20(4):2670-2679. doi: 10.1002/alz.13718. Epub 2024 Feb 21. Alzheimers Dement. 2024. PMID: 38380866 Free PMC article.
A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.
Rajabli F, Beecham GW, Hendrie HC, Baiyewu O, Ogunniyi A, Gao S, Kushch NA, Lipkin-Vasquez M, Hamilton-Nelson KL, Young JI, Dykxhoorn DM, Nuytemans K, Kunkle BW, Wang L, Jin F, Liu X, Feliciano-Astacio BE; Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Genetic Consortium; Schellenberg GD, Dalgard CL, Griswold AJ, Byrd GS, Reitz C, Cuccaro ML, Haines JL, Pericak-Vance MA, Vance JM. Rajabli F, et al. Among authors: byrd gs. PLoS Genet. 2022 Jul 5;18(7):e1009977. doi: 10.1371/journal.pgen.1009977. eCollection 2022 Jul. PLoS Genet. 2022. PMID: 35788729 Free PMC article.
53 results