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Characterizing Enoxaparin's Population Pharmacokinetics to Guide Dose Individualization in the Pediatric Population.
Carreño FO, Gerhart JG, Helfer VE, Sinha J, Kumar KR, Kirkpatrick C, Hornik CP, Gonzalez D; Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. Carreño FO, et al. Among authors: hornik cp. Clin Pharmacokinet. 2024 Jul;63(7):999-1014. doi: 10.1007/s40262-024-01388-x. Epub 2024 Jul 2. Clin Pharmacokinet. 2024. PMID: 38955947
Development and Evaluation of a Virtual Population of Children with Obesity for Physiologically Based Pharmacokinetic Modeling.
Gerhart JG, Carreño FO, Edginton AN, Sinha J, Perrin EM, Kumar KR, Rikhi A, Hornik CP, Harris V, Ganguly S, Cohen-Wolkowiez M, Gonzalez D; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: hornik cp. Clin Pharmacokinet. 2022 Feb;61(2):307-320. doi: 10.1007/s40262-021-01072-4. Epub 2021 Oct 7. Clin Pharmacokinet. 2022. PMID: 34617262 Free PMC article.
Application of Physiologically Based Pharmacokinetic Modeling to Characterize the Effects of Age and Obesity on the Disposition of Levetiracetam in the Pediatric Population.
Maglalang PD, Sinha J, Zimmerman K, McCann S, Edginton A, Hornik CP, Hornik CD, Muller WJ, Al-Uzri A, Meyer M, Chen JY, Anand R, Perrin EM, Gonzalez D; Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. Maglalang PD, et al. Among authors: hornik cp. Clin Pharmacokinet. 2024 Jun;63(6):885-899. doi: 10.1007/s40262-024-01367-2. Epub 2024 May 30. Clin Pharmacokinet. 2024. PMID: 38814425
Population Pharmacokinetics of Milrinone in Infants, Children, and Adolescents.
Hornik CP, Yogev R, Mourani PM, Watt KM, Sullivan JE, Atz AM, Speicher D, Al-Uzri A, Adu-Darko M, Payne EH, Gelber CE, Lin S, Harper B, Melloni C, Cohen-Wolkowiez M, Gonzalez D; Best Pharmaceuticals for Children Act-Pediatric Trials Network Steering Committee. Hornik CP, et al. J Clin Pharmacol. 2019 Dec;59(12):1606-1619. doi: 10.1002/jcph.1499. Epub 2019 Jul 17. J Clin Pharmacol. 2019. PMID: 31317556 Free PMC article.
Population Pharmacokinetics of Metoclopramide in Infants, Children, and Adolescents.
Ge S, Mendley SR, Gerhart JG, Melloni C, Hornik CP, Sullivan JE, Atz A, Delmore P, Tremoulet A, Harper B, Payne E, Lin S, Erinjeri J, Cohen-Wolkowiez M, Gonzalez D; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Ge S, et al. Among authors: hornik cp. Clin Transl Sci. 2020 Nov;13(6):1189-1198. doi: 10.1111/cts.12803. Epub 2020 May 27. Clin Transl Sci. 2020. PMID: 32324313 Free PMC article.
Simulated Assessment of Pharmacokinetically Guided Dosing for Investigational Treatments of Pediatric Patients With Coronavirus Disease 2019.
Maharaj AR, Wu H, Hornik CP, Balevic SJ, Hornik CD, Smith PB, Gonzalez D, Zimmerman KO, Benjamin DK Jr, Cohen-Wolkowiez M; Best Pharmaceuticals for Children Act–Pediatric Trials Network Steering Committee. Maharaj AR, et al. Among authors: hornik cp, hornik cd. JAMA Pediatr. 2020 Oct 1;174(10):e202422. doi: 10.1001/jamapediatrics.2020.2422. Epub 2020 Oct 5. JAMA Pediatr. 2020. PMID: 32501511 Free PMC article.
External Evaluation of Two Pediatric Population Pharmacokinetics Models of Oral Trimethoprim and Sulfamethoxazole.
Wu YSS, Cohen-Wolkowiez M, Hornik CP, Gerhart JG, Autmizguine J, Cobbaert M, Gonzalez D; Best Pharmaceuticals for Children Act—Pediatric Trials Network Steering Committee. Wu YSS, et al. Among authors: hornik cp. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0214920. doi: 10.1128/AAC.02149-20. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33903114 Free PMC article.
Use of Real-World Data and Physiologically-Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity.
Gerhart JG, Carreño FO, Loop MS, Lee CR, Edginton AN, Sinha J, Kumar KR, Kirkpatrick CM, Hornik CP, Gonzalez D; Best Pharmaceuticals for Children Act - Pediatric Trials Network Steering Committee. Gerhart JG, et al. Among authors: hornik cp. Clin Pharmacol Ther. 2022 Aug;112(2):391-403. doi: 10.1002/cpt.2618. Epub 2022 May 18. Clin Pharmacol Ther. 2022. PMID: 35451072 Free PMC article.
254 results