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Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice.
Zumerle S, Sarill M, Saponaro M, Colucci M, Contu L, Lazzarini E, Sartori R, Pezzini C, Rinaldi A, Scanu A, Sgrignani J, Locatelli P, Sabbadin M, Valdata A, Brina D, Giacomini I, Rizzo B, Pierantoni A, Sharifi S, Bressan S, Altomare C, Goshovska Y, Giraudo C, Luisetto R, Iaccarino L, Torcasio C, Mosole S, Pasquini E, Rinaldi A, Pellegrini L, Peron G, Fassan M, Masiero S, Giori AM, Dall'Acqua S, Auwerx J, Cippà P, Cavalli A, Bolis M, Sandri M, Barile L, Montopoli M, Alimonti A. Zumerle S, et al. Among authors: rinaldi a. Nat Aging. 2024 Sep;4(9):1231-1248. doi: 10.1038/s43587-024-00663-7. Epub 2024 Jul 1. Nat Aging. 2024. PMID: 38951692 Free PMC article.
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.
Bernasocchi T, El Tekle G, Bolis M, Mutti A, Vallerga A, Brandt LP, Spriano F, Svinkina T, Zoma M, Ceserani V, Rinaldi A, Janouskova H, Bossi D, Cavalli M, Mosole S, Geiger R, Dong Z, Yang CG, Albino D, Rinaldi A, Schraml P, Linder S, Carbone GM, Alimonti A, Bertoni F, Moch H, Carr SA, Zwart W, Kruithof-de Julio M, Rubin MA, Udeshi ND, Theurillat JP. Bernasocchi T, et al. Among authors: rinaldi a. Nat Commun. 2021 Feb 2;12(1):734. doi: 10.1038/s41467-020-20820-x. Nat Commun. 2021. PMID: 33531470 Free PMC article.
Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.
Troiani M, Colucci M, D'Ambrosio M, Guccini I, Pasquini E, Varesi A, Valdata A, Mosole S, Revandkar A, Attanasio G, Rinaldi A, Rinaldi A, Bolis M, Cippà P, Alimonti A. Troiani M, et al. Among authors: rinaldi a. Nat Commun. 2022 Apr 21;13(1):2177. doi: 10.1038/s41467-022-29824-1. Nat Commun. 2022. PMID: 35449130 Free PMC article.
Author Correction: Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.
Troiani M, Colucci M, D'Ambrosio M, Guccini I, Pasquini E, Varesi A, Valdata A, Mosole S, Revandkar A, Attanasio G, Rinaldi A, Rinaldi A, Bolis M, Cippà P, Alimonti A. Troiani M, et al. Among authors: rinaldi a. Nat Commun. 2023 Jul 20;14(1):4386. doi: 10.1038/s41467-023-40080-9. Nat Commun. 2023. PMID: 37474528 Free PMC article. No abstract available.
A transfer learning framework to elucidate the clinical relevance of altered proximal tubule cell states in kidney disease.
Legouis D, Rinaldi A, Malpetti D, Arnoux G, Verissimo T, Faivre A, Mangili F, Rinaldi A, Ruinelli L, Pugin J, Moll S, Clivio L, Bolis M, de Seigneux S, Azzimonti L, Cippà PE. Legouis D, et al. Among authors: rinaldi a. iScience. 2024 Feb 22;27(3):109271. doi: 10.1016/j.isci.2024.109271. eCollection 2024 Mar 15. iScience. 2024. PMID: 38487013 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 38502560
SOX9 switch links regeneration to fibrosis at the single-cell level in mammalian kidneys.
Aggarwal S, Wang Z, Rincon Fernandez Pacheco D, Rinaldi A, Rajewski A, Callemeyn J, Van Loon E, Lamarthée B, Covarrubias AE, Hou J, Yamashita M, Akiyama H, Karumanchi SA, Svendsen CN, Noble PW, Jordan SC, Breunig JJ, Naesens M, Cippà PE, Kumar S. Aggarwal S, et al. Among authors: rinaldi a. Science. 2024 Feb 23;383(6685):eadd6371. doi: 10.1126/science.add6371. Epub 2024 Feb 23. Science. 2024. PMID: 38386758 Free PMC article.
Spatiotemporal Landscape of Kidney Tubular Responses to Glomerular Proteinuria.
Faivre A, Bugarski M, Rinaldi A, Sakhi IB, Verissimo T, Legouis D, Rutkowski JM, Correia S, Kaminska M, Dalga D, Malpetti D, Cippa PE, de Seigneux S, Hall AM. Faivre A, et al. Among authors: rinaldi a. J Am Soc Nephrol. 2024 Jul 1;35(7):854-869. doi: 10.1681/ASN.0000000000000357. Epub 2024 Apr 23. J Am Soc Nephrol. 2024. PMID: 38652545
1,026 results