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Page 1
Targeting senescence induced by age or chemotherapy with a polyphenol-rich natural extract improves longevity and healthspan in mice.
Zumerle S, Sarill M, Saponaro M, Colucci M, Contu L, Lazzarini E, Sartori R, Pezzini C, Rinaldi A, Scanu A, Sgrignani J, Locatelli P, Sabbadin M, Valdata A, Brina D, Giacomini I, Rizzo B, Pierantoni A, Sharifi S, Bressan S, Altomare C, Goshovska Y, Giraudo C, Luisetto R, Iaccarino L, Torcasio C, Mosole S, Pasquini E, Rinaldi A, Pellegrini L, Peron G, Fassan M, Masiero S, Giori AM, Dall'Acqua S, Auwerx J, Cippà P, Cavalli A, Bolis M, Sandri M, Barile L, Montopoli M, Alimonti A. Zumerle S, et al. Among authors: alimonti a. Nat Aging. 2024 Sep;4(9):1231-1248. doi: 10.1038/s43587-024-00663-7. Epub 2024 Jul 1. Nat Aging. 2024. PMID: 38951692 Free PMC article.
In and out from senescence.
Zumerle S, Alimonti A. Zumerle S, et al. Among authors: alimonti a. Nat Cell Biol. 2020 Jul;22(7):753-754. doi: 10.1038/s41556-020-0540-x. Nat Cell Biol. 2020. PMID: 32591745 No abstract available.
Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.
Troiani M, Colucci M, D'Ambrosio M, Guccini I, Pasquini E, Varesi A, Valdata A, Mosole S, Revandkar A, Attanasio G, Rinaldi A, Rinaldi A, Bolis M, Cippà P, Alimonti A. Troiani M, et al. Among authors: alimonti a. Nat Commun. 2022 Apr 21;13(1):2177. doi: 10.1038/s41467-022-29824-1. Nat Commun. 2022. PMID: 35449130 Free PMC article.
Epiregulation of the SASP makes good neighbors.
Desbats MA, Zumerle S, Alimonti A. Desbats MA, et al. Among authors: alimonti a. Nat Aging. 2021 May;1(5):420-421. doi: 10.1038/s43587-021-00068-w. Nat Aging. 2021. PMID: 37118016 No abstract available.
Author Correction: Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer.
Troiani M, Colucci M, D'Ambrosio M, Guccini I, Pasquini E, Varesi A, Valdata A, Mosole S, Revandkar A, Attanasio G, Rinaldi A, Rinaldi A, Bolis M, Cippà P, Alimonti A. Troiani M, et al. Among authors: alimonti a. Nat Commun. 2023 Jul 20;14(1):4386. doi: 10.1038/s41467-023-40080-9. Nat Commun. 2023. PMID: 37474528 Free PMC article. No abstract available.
The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells.
Brina D, Ponzoni A, Troiani M, Calì B, Pasquini E, Attanasio G, Mosole S, Mirenda M, D'Ambrosio M, Colucci M, Guccini I, Revandkar A, Alajati A, Tebaldi T, Donzel D, Lauria F, Parhizgari N, Valdata A, Maddalena M, Calcinotto A, Bolis M, Rinaldi A, Barry S, Rüschoff JH, Sabbadin M, Sumanasuriya S, Crespo M, Sharp A, Yuan W, Grinu M, Boyle A, Miller C, Trotman L, Delaleu N, Fassan M, Moch H, Viero G, de Bono J, Alimonti A. Brina D, et al. Among authors: alimonti a. Nat Cancer. 2023 Aug;4(8):1102-1121. doi: 10.1038/s43018-023-00594-z. Epub 2023 Jul 17. Nat Cancer. 2023. PMID: 37460872 Free PMC article.
Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.
Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, Bono J, Carracedo A, Alimonti A. Chen J, et al. Among authors: alimonti a. Nat Genet. 2018 Feb;50(2):219-228. doi: 10.1038/s41588-017-0026-3. Epub 2018 Jan 15. Nat Genet. 2018. PMID: 29335542 Free PMC article.
Publisher Correction: Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer.
Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, de Bono J, Carracedo A, Alimonti A. Chen J, et al. Among authors: alimonti a. Nat Genet. 2018 Sep;50(9):1343. doi: 10.1038/s41588-018-0181-1. Nat Genet. 2018. PMID: 30089860
225 results