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Oncogene-induced TIM-3 ligand expression dictates susceptibility to anti-TIM-3 therapy in mice.
Talvard-Balland N, Braun LM, Dixon KO, Zwick M, Engel H, Hartmann A, Duquesne S, Penter L, Andrieux G, Rindlisbacher L, Acerbis A, Ehmann J, Köllerer C, Ansuinelli M, Rettig A, Moschallski K, Apostolova P, Brummer T, Illert AL, Schramm MA, Cheng Y, Köttgen A, Duyster J, Menssen HD, Ritz J, Blazar BR, Boerries M, Schmitt-Gräff A, Sariipek N, Van Galen P, Buescher JM, Cabezas-Wallscheid N, Pahl HL, Pearce EL, Soiffer RJ, Wu CJ, Vago L, Becher B, Köhler N, Wertheimer T, Kuchroo VK, Zeiser R. Talvard-Balland N, et al. Among authors: schramm ma. J Clin Invest. 2024 Jun 25;134(16):e177460. doi: 10.1172/JCI177460. J Clin Invest. 2024. PMID: 38916965 Free PMC article.
TIM-3 restrains anti-tumour immunity by regulating inflammasome activation.
Dixon KO, Tabaka M, Schramm MA, Xiao S, Tang R, Dionne D, Anderson AC, Rozenblatt-Rosen O, Regev A, Kuchroo VK. Dixon KO, et al. Among authors: schramm ma. Nature. 2021 Jul;595(7865):101-106. doi: 10.1038/s41586-021-03626-9. Epub 2021 Jun 9. Nature. 2021. PMID: 34108686 Free PMC article.
Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion.
Zhu C, Dixon KO, Newcomer K, Gu G, Xiao S, Zaghouani S, Schramm MA, Wang C, Zhang H, Goto K, Christian E, Rangachari M, Rosenblatt-Rosen O, Okada H, Mak T, Singer M, Regev A, Kuchroo V. Zhu C, et al. Among authors: schramm ma. Sci Adv. 2021 Apr 30;7(18):eabd2710. doi: 10.1126/sciadv.abd2710. Print 2021 Apr. Sci Adv. 2021. PMID: 33931442 Free PMC article.
Induction of a colitogenic phenotype in Th1-like cells depends on interleukin-23 receptor signaling.
Pawlak M, DeTomaso D, Schnell A, Meyer Zu Horste G, Lee Y, Nyman J, Dionne D, Regan BML, Singh V, Delorey T, Schramm MA, Wang C, Wallrapp A, Burkett PR, Riesenfeld SJ, Anderson AC, Regev A, Xavier RJ, Yosef N, Kuchroo VK. Pawlak M, et al. Among authors: schramm ma. Immunity. 2022 Sep 13;55(9):1663-1679.e6. doi: 10.1016/j.immuni.2022.08.007. Epub 2022 Sep 6. Immunity. 2022. PMID: 36070768 Free PMC article.
Burden of disease and impact on quality of life in chronic back pain - a comparative cross-sectional study of 150 axial spondyloarthritis and 150 orthopedic back pain patients.
Frede N, Hiestand S, Endres D, van Elst LT, Finzel S, Chevalier N, Schramm MA, Rump IC, Thiel J, Voll R, Herget G, Venhoff N. Frede N, et al. Among authors: schramm ma. Front Med (Lausanne). 2023 Aug 17;10:1221087. doi: 10.3389/fmed.2023.1221087. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37663655 Free PMC article.
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