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Inhibition of the Eukaryotic Initiation Factor-2-α Kinase PERK Decreases Risk of Autoimmune Diabetes in Mice.
Muralidharan C, Huang F, Enriquez JR, Wang JE, Nelson JB, Nargis T, May SC, Chakraborty A, Figatner KT, Navitskaya S, Anderson CM, Calvo V, Surguladze D, Mulvihill MJ, Yi X, Sarkar S, Oakes SA, Webb-Robertson BM, Sims EK, Staschke KA, Eizirik DL, Nakayasu ES, Stokes ME, Tersey SA, Mirmira RG. Muralidharan C, et al. Among authors: sarkar s. bioRxiv [Preprint]. 2024 Jun 3:2023.10.06.561126. doi: 10.1101/2023.10.06.561126. bioRxiv. 2024. Update in: J Clin Invest. 2024 Jun 18;134(16):e176136. doi: 10.1172/JCI176136 PMID: 38895427 Free PMC article. Updated. Preprint.
GDF15: a potential therapeutic target for type 1 diabetes.
Sarkar S, Melchior JT, Henry HR, Syed F, Mirmira RG, Nakayasu ES, Metz TO. Sarkar S, et al. Expert Opin Ther Targets. 2022 Jan;26(1):57-67. doi: 10.1080/14728222.2022.2029410. Epub 2022 Feb 9. Expert Opin Ther Targets. 2022. PMID: 35138971 Free PMC article. Review.
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response.
Sarkar S, Elliott EC, Henry HR, Ludovico ID, Melchior JT, Frazer-Abel A, Webb-Robertson BJ, Davidson WS, Holers VM, Rewers MJ, Metz TO, Nakayasu ES. Sarkar S, et al. medRxiv [Preprint]. 2023 Feb 22:2023.02.21.23286132. doi: 10.1101/2023.02.21.23286132. medRxiv. 2023. Update in: Clin Proteomics. 2023 Sep 21;20(1):38. doi: 10.1186/s12014-023-09429-6 PMID: 36865103 Free PMC article. Updated. Preprint.
Fatty acid-mediated signaling as a target for developing type 1 diabetes therapies.
Díaz Ludovico I, Sarkar S, Elliott E, Virtanen SM, Erlund I, Ramanadham S, Mirmira RG, Metz TO, Nakayasu ES. Díaz Ludovico I, et al. Among authors: sarkar s. Expert Opin Ther Targets. 2023 Jul-Dec;27(9):793-806. doi: 10.1080/14728222.2023.2259099. Epub 2023 Sep 14. Expert Opin Ther Targets. 2023. PMID: 37706269 Free PMC article. Review.
Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes.
Sims EK, Kulkarni A, Hull A, Woerner SE, Cabrera S, Mastrandrea LD, Hammoud B, Sarkar S, Nakayasu ES, Mastracci TL, Perkins SM, Ouyang F, Webb-Robertson BJ, Enriquez JR, Tersey SA, Evans-Molina C, Long SA, Blanchfield L, Gerner EW, Mirmira RG, DiMeglio LA. Sims EK, et al. Among authors: sarkar s. Cell Rep Med. 2023 Nov 21;4(11):101261. doi: 10.1016/j.xcrm.2023.101261. Epub 2023 Nov 1. Cell Rep Med. 2023. PMID: 37918404 Free PMC article. Clinical Trial.
A proteomic meta-analysis refinement of plasma extracellular vesicles.
Vallejo MC, Sarkar S, Elliott EC, Henry HR, Powell SM, Diaz Ludovico I, You Y, Huang F, Payne SH, Ramanadham S, Sims EK, Metz TO, Mirmira RG, Nakayasu ES. Vallejo MC, et al. Among authors: sarkar s. Sci Data. 2023 Nov 28;10(1):837. doi: 10.1038/s41597-023-02748-1. Sci Data. 2023. PMID: 38017024 Free PMC article.
Protection of β cells against pro-inflammatory cytokine stress by the GDF15-ERBB2 signaling.
Sarkar S, Syed F, Webb-Robertson BJ, Melchior JT, Chang G, Gritsenko M, Wang YT, Tsai CF, Liu J, Yi X, Cui Y, Eizirik DL, Metz TO, Rewers M, Evans-Molina C, Mirmira RG, Nakayasu ES. Sarkar S, et al. medRxiv [Preprint]. 2023 Nov 27:2023.11.27.23298904. doi: 10.1101/2023.11.27.23298904. medRxiv. 2023. PMID: 38076918 Free PMC article. Preprint.
A fast and sensitive size-exclusion chromatography method for plasma extracellular vesicle proteomic analysis.
Ludovico ID, Powell SM, Many G, Bramer L, Sarkar S, Stratton K, Liu T, Shi T, Qian WJ, Burnum-Johnson KE, Melchior JT, Nakayasu ES. Ludovico ID, et al. Among authors: sarkar s. bioRxiv [Preprint]. 2024 Jan 20:2024.01.17.576135. doi: 10.1101/2024.01.17.576135. bioRxiv. 2024. Update in: Proteomics. 2024 Aug;24(16):e2400025. doi: 10.1002/pmic.202400025 PMID: 38293231 Free PMC article. Updated. Preprint.
6,373 results