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Inhibition of the Eukaryotic Initiation Factor-2-α Kinase PERK Decreases Risk of Autoimmune Diabetes in Mice.
Muralidharan C, Huang F, Enriquez JR, Wang JE, Nelson JB, Nargis T, May SC, Chakraborty A, Figatner KT, Navitskaya S, Anderson CM, Calvo V, Surguladze D, Mulvihill MJ, Yi X, Sarkar S, Oakes SA, Webb-Robertson BM, Sims EK, Staschke KA, Eizirik DL, Nakayasu ES, Stokes ME, Tersey SA, Mirmira RG. Muralidharan C, et al. Among authors: oakes sa. bioRxiv [Preprint]. 2024 Jun 3:2023.10.06.561126. doi: 10.1101/2023.10.06.561126. bioRxiv. 2024. Update in: J Clin Invest. 2024 Jun 18;134(16):e176136. doi: 10.1172/JCI176136 PMID: 38895427 Free PMC article. Updated. Preprint.
Inhibition of the eukaryotic initiation factor-2α kinase PERK decreases risk of autoimmune diabetes in mice.
Muralidharan C, Huang F, Enriquez JR, Wang JE, Nelson JB, Nargis T, May SC, Chakraborty A, Figatner KT, Navitskaya S, Anderson CM, Calvo V, Surguladze D, Mulvihill MJ, Yi X, Sarkar S, Oakes SA, Webb-Robertson BM, Sims EK, Staschke KA, Eizirik DL, Nakayasu ES, Stokes ME, Tersey SA, Mirmira RG. Muralidharan C, et al. Among authors: oakes sa. J Clin Invest. 2024 Jun 18;134(16):e176136. doi: 10.1172/JCI176136. J Clin Invest. 2024. PMID: 38889047 Free PMC article.
SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells.
Nguyen LC, Renner DM, Silva D, Yang D, Parenti N, Medina KM, Nicolaescu V, Gula H, Drayman N, Valdespino A, Mohamed A, Dann C, Wannemo K, Robinson-Mailman L, Gonzalez A, Stock L, Cao M, Qiao Z, Moellering RE, Tay S, Randall G, Beers MF, Rosner MR, Oakes SA, Weiss SR. Nguyen LC, et al. Among authors: oakes sa. bioRxiv [Preprint]. 2022 Jun 13:2021.12.30.474519. doi: 10.1101/2021.12.30.474519. bioRxiv. 2022. Update in: mBio. 2022 Oct 26;13(5):e0241522. doi: 10.1128/mbio.02415-22 PMID: 35821981 Free PMC article. Updated. Preprint.
Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response.
Nguyen LC, Yang D, Nicolaescu V, Best TJ, Ohtsuki T, Chen SN, Friesen JB, Drayman N, Mohamed A, Dann C, Silva D, Gula H, Jones KA, Millis JM, Dickinson BC, Tay S, Oakes SA, Pauli GF, Meltzer DO, Randall G, Rosner MR. Nguyen LC, et al. Among authors: oakes sa. bioRxiv [Preprint]. 2021 Mar 10:2021.03.10.432967. doi: 10.1101/2021.03.10.432967. bioRxiv. 2021. Update in: Sci Adv. 2022 Feb 25;8(8):eabi6110. doi: 10.1126/sciadv.abi6110 PMID: 33758843 Free PMC article. Updated. Preprint.
Inflammation-Induced Claudin-2 Upregulation Limits Pancreatitis Progression by Enhancing Tight Junction-Controlled Pancreatic Ductal Transport.
Kesaraju S, Li Y, Xing J, Tracy M, Wannemo K, Holder A, Zhao P, Khan MA, Kainov J, Rana N, Sidahmed M, Hyoju S, Smith L, Matthews J, Tay S, Khalili-Araghi F, Rana M, Oakes SA, Shen L, Weber CR. Kesaraju S, et al. Among authors: oakes sa. bioRxiv [Preprint]. 2024 Nov 13:2023.09.01.555960. doi: 10.1101/2023.09.01.555960. bioRxiv. 2024. PMID: 39605652 Free PMC article. Preprint.
Unfolding emergency calls stress granules to the ER.
Pincus D, Oakes SA. Pincus D, et al. Among authors: oakes sa. Nat Cell Biol. 2024 Jun;26(6):845-846. doi: 10.1038/s41556-024-01434-7. Nat Cell Biol. 2024. PMID: 38822214 No abstract available.
Stress and human health in diabetes: A report from the 19th Chicago Biomedical Consortium symposium.
Mirmira RG, Kulkarni RN, Xu P, Drossos T, Varady K, Knutson KL, Reutrakul S, Martyn-Nemeth P, Sargis RM, Wallia A, Tuchman AM, Weissberg-Benchell J, Danielson KK, Oakes SA, Thomas CC, Layden BT, May SC, Burbea Hoffmann M, Gatta E, Solway J, Philipson LH. Mirmira RG, et al. Among authors: oakes sa. J Clin Transl Sci. 2023 Nov 20;7(1):e263. doi: 10.1017/cts.2023.646. eCollection 2023. J Clin Transl Sci. 2023. PMID: 38229904 Free PMC article.
61 results