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Limitations in mitochondrial programming restrain the differentiation and maturation of human stem cell-derived β cells.
Lietzke AC, Bealer E, Crumley K, King J, Stendahl AM, Zhu J, Pearson GL, Levi-D'Ancona E, Henry-Kanarek B, Reck EC, Arnipalli M, Sidarala V, Walker EM, Pennathur S, Madsen JGS, Shea LD, Soleimanpour SA. Lietzke AC, et al. Among authors: sidarala v. bioRxiv [Preprint]. 2024 Jul 29:2024.07.26.605318. doi: 10.1101/2024.07.26.605318. bioRxiv. 2024. PMID: 39211191 Free PMC article. Preprint.
LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes.
Li J, Zhu J, Deng Y, Reck EC, Walker EM, Sidarala V, Hubers DL, Pasmooij MB, Shin CS, Bandesh K, Motakis E, Nargund S, Kursawe R, Basrur V, Nesvizhskii AI, Stitzel ML, Chan DC, Soleimanpour SA. Li J, et al. Among authors: sidarala v. bioRxiv [Preprint]. 2024 Jun 3:2024.06.03.597215. doi: 10.1101/2024.06.03.597215. bioRxiv. 2024. PMID: 38895283 Free PMC article. Preprint.
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis.
Arunagiri A, Alam M, Haataja L, Draz H, Alasad B, Samy P, Sadique N, Tong Y, Cai Y, Shakeri H, Fantuzzi F, Ibrahim H, Jang I, Sidarala V, Soleimanpour SA, Satin LS, Otonkoski T, Cnop M, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Arunagiri A, et al. Among authors: sidarala v. Protein Sci. 2024 Apr;33(4):e4949. doi: 10.1002/pro.4949. Protein Sci. 2024. PMID: 38511500 Free PMC article.
β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes.
Skovsø S, Overby P, Memar-Zadeh J, Lee JTC, Yang JCC, Shanina I, Sidarala V, Levi-D'Ancona E, Zhu J, Soleimanpour SA, Horwitz MS, Johnson JD. Skovsø S, et al. Among authors: sidarala v. Endocrinology. 2022 Oct 11;163(11):bqac144. doi: 10.1210/endocr/bqac144. Endocrinology. 2022. PMID: 36048448 Free PMC article.
19 results