Sims EK - Search Results

1

Inhibition of the eukaryotic initiation factor-2α kinase PERK decreases risk of autoimmune diabetes in mice.

Muralidharan C, Huang F, Enriquez JR, Wang JE, Nelson JB, Nargis T, May SC, Chakraborty A, Figatner KT, Navitskaya S, Anderson CM, Calvo V, Surguladze D, Mulvihill MJ, Yi X, Sarkar S, Oakes SA, Webb-Robertson BM, Sims EK, Staschke KA, Eizirik DL, Nakayasu ES, Stokes ME, Tersey SA, Mirmira RG. Muralidharan C, et al. Among authors: sims ek. J Clin Invest. 2024 Jun 18;134(16):e176136. doi: 10.1172/JCI176136. J Clin Invest. 2024. PMID: 38889047 Free PMC article.

2

Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains.

Sims EK, Hatanaka M, Morris DL, Tersey SA, Kono T, Chaudry ZZ, Day KH, Moss DR, Stull ND, Mirmira RG, Evans-Molina C. Sims EK, et al. Am J Physiol Endocrinol Metab. 2013 Dec;305(12):E1495-511. doi: 10.1152/ajpendo.00366.2013. Epub 2013 Oct 29. Am J Physiol Endocrinol Metab. 2013. PMID: 24169046 Free PMC article.

3

Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway.

Hatanaka M, Maier B, Sims EK, Templin AT, Kulkarni RN, Evans-Molina C, Mirmira RG. Hatanaka M, et al. Among authors: sims ek. Diabetes. 2014 Oct;63(10):3404-15. doi: 10.2337/db14-0105. Epub 2014 May 16. Diabetes. 2014. PMID: 24834975 Free PMC article.

4

Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes.

Sims EK, Chaudhry Z, Watkins R, Syed F, Blum J, Ouyang F, Perkins SM, Mirmira RG, Sosenko J, DiMeglio LA, Evans-Molina C. Sims EK, et al. Diabetes Care. 2016 Sep;39(9):1519-26. doi: 10.2337/dc15-2849. Epub 2016 Jul 6. Diabetes Care. 2016. PMID: 27385327 Free PMC article. Clinical Trial.

5

Biomarkers of β-Cell Stress and Death in Type 1 Diabetes.

Mirmira RG, Sims EK, Syed F, Evans-Molina C. Mirmira RG, et al. Among authors: sims ek. Curr Diab Rep. 2016 Oct;16(10):95. doi: 10.1007/s11892-016-0783-x. Curr Diab Rep. 2016. PMID: 27541297 Free PMC article. Review.

6

Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation.

Hatanaka M, Anderson-Baucum E, Lakhter A, Kono T, Maier B, Tersey SA, Tanizawa Y, Evans-Molina C, Mirmira RG, Sims EK. Hatanaka M, et al. Among authors: sims ek. Sci Rep. 2017 Jun 19;7(1):3758. doi: 10.1038/s41598-017-03869-5. Sci Rep. 2017. PMID: 28630491 Free PMC article.

7

Immune reconstitution in ART treated, but not untreated HIV infection, is associated with abnormal beta cell function.

Sims EK, Park G, Mather KJ, Mirmira RG, Liu Z, Gupta SK. Sims EK, et al. PLoS One. 2018 May 24;13(5):e0197080. doi: 10.1371/journal.pone.0197080. eCollection 2018. PLoS One. 2018. PMID: 29795574 Free PMC article.

8

Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes.

Neyman A, Nelson J, Tersey SA, Mirmira RG, Evans-Molina C, Sims EK. Neyman A, et al. Among authors: sims ek. Diabetes Obes Metab. 2019 Jan;21(1):95-102. doi: 10.1111/dom.13489. Epub 2018 Aug 24. Diabetes Obes Metab. 2019. PMID: 30073765 Free PMC article.

9

Biomarkers of islet beta cell stress and death in type 1 diabetes.

Sims EK, Evans-Molina C, Tersey SA, Eizirik DL, Mirmira RG. Sims EK, et al. Diabetologia. 2018 Nov;61(11):2259-2265. doi: 10.1007/s00125-018-4712-1. Epub 2018 Aug 15. Diabetologia. 2018. PMID: 30112687 Free PMC article. Review.

10

Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes.

Ocaña GJ, Sims EK, Watkins RA, Ragg S, Mather KJ, Oram RA, Mirmira RG, DiMeglio LA, Blum JS, Evans-Molina C. Ocaña GJ, et al. Among authors: sims ek. PLoS One. 2019 Jan 10;14(1):e0208456. doi: 10.1371/journal.pone.0208456. eCollection 2019. PLoS One. 2019. PMID: 30629603 Free PMC article.

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