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The response of Canada's clinical health research ecosystem to the COVID-19 pandemic.
Lamontagne F, Masse MH, Yarnell C, Camirand-Lemyre F, Lévesque S, Domingue MP, O'Hearn K, Watpool I, Hoogenes J, Sprague S, Ménard J, Lemaire-Paquette S, Hébert-Dufresne L, Cook D, Hébert P, Rowan K, Yada N, Menon K, Fowler R, Fox-Robichaud A, Boutin D, Marshall J, Kho ME; Canadian Clinical Research Network (CCRN), the Canadian Critical Care Trials Group (CCCTG) and Sepsis Canada. Lamontagne F, et al. Among authors: rowan k. CMAJ. 2024 Jun 16;196(23):E779-E788. doi: 10.1503/cmaj.230760. CMAJ. 2024. PMID: 38885975 Free PMC article.
Simvastatin in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Horvat C, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. REMAP-CAP Investigators, et al. Among authors: rowan km. N Engl J Med. 2023 Dec 21;389(25):2341-2354. doi: 10.1056/NEJMoa2309995. Epub 2023 Oct 25. N Engl J Med. 2023. PMID: 37888913 Free PMC article. Clinical Trial.
Adjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis.
Arabi YM, Al-Hameed F, Burns KEA, Mehta S, Alsolamy SJ, Alshahrani MS, Mandourah Y, Almekhlafi GA, Almaani M, Al Bshabshe A, Finfer S, Arshad Z, Khalid I, Mehta Y, Gaur A, Hawa H, Buscher H, Lababidi H, Al Aithan A, Abdukahil SAI, Jose J, Afesh LY, Al-Dawood A; Saudi Critical Care Trials Group. Arabi YM, et al. N Engl J Med. 2019 Apr 4;380(14):1305-1315. doi: 10.1056/NEJMoa1816150. Epub 2019 Feb 18. N Engl J Med. 2019. PMID: 30779530 Clinical Trial.
Heterogeneity in the Effect of Early Goal-Directed Therapy for Septic Shock: A Secondary Analysis of Two Multicenter International Trials.
Shah FA, Talisa VB, Chang CH, Triantafyllou S, Tang L, Mayr FB, Higgins AM, Peake SL, Mouncey P, Harrison DA, DeMerle KM, Kennedy JN, Cooper GF, Bellomo R, Rowan K, Yealy DM, Seymour CW, Angus DC, Yende SP. Shah FA, et al. Among authors: rowan k. Crit Care Med. 2024 Oct 23. doi: 10.1097/CCM.0000000000006463. Online ahead of print. Crit Care Med. 2024. PMID: 39440873
Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis.
Baillie JK, Angus D, Burnham K, Calandra T, Calfee C, Gutteridge A, Hacohen N, Khatri P, Langley R, Ma'ayan A, Marshall J, Maslove D, Prescott HC, Rowan K, Scicluna BP, Seymour C, Shankar-Hari M, Shapiro N, Joost Wiersinga W, Singer M, Randolph AG. Baillie JK, et al. Among authors: rowan k. Intensive Care Med. 2024 Oct 21:10.1007/s00134-024-07665-4. doi: 10.1007/s00134-024-07665-4. Online ahead of print. Intensive Care Med. 2024. PMID: 39432104 Free PMC article. Review.
Guidance to inform research recruitment processes for studies involving critically ill patients.
Woolfall K, Paddock K, Watkins M, Kearney A, Neville K, Frith L, Welters I, Gamble C, Trinder J, Pattison N, White C, Brett S, Dilworth S, Ross M, Mouncey P, Rowan K, Dawson A, Collet C, Walsh T, Young B. Woolfall K, et al. Among authors: rowan k. J Intensive Care Soc. 2024 Feb;25(1):95-101. doi: 10.1177/17511437231197293. Epub 2023 Sep 8. J Intensive Care Soc. 2024. PMID: 39323597 Free PMC article.
478 results