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Addendum: A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase.
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL Jr, Robbins N, Nodwell J, Whitesell L, Cowen LE. MacAlpine J, et al. Among authors: daniel ivad m. Nat Commun. 2024 Aug 1;15(1):6440. doi: 10.1038/s41467-024-50740-z. Nat Commun. 2024. PMID: 39090082 Free PMC article. No abstract available.
Reply to: Lactobacillus species do not produce 1-acetyl-β-carboline.
MacAlpine J, Daniel-Ivad M, Atere D, Laflamme B, Robbins N, Navarre WW, Nodwell J, Whitesell L, Cowen LE. MacAlpine J, et al. Among authors: daniel ivad m. Nat Commun. 2024 Aug 1;15(1):6441. doi: 10.1038/s41467-024-50684-4. Nat Commun. 2024. PMID: 39090077 Free PMC article. No abstract available.
A metabolomics pipeline highlights microbial metabolism in bloodstream infections.
Mayers JR, Varon J, Zhou RR, Daniel-Ivad M, Beaulieu C, Bhosle A, Glasser NR, Lichtenauer FM, Ng J, Vera MP, Huttenhower C, Perrella MA, Clish CB, Zhao SD, Baron RM, Balskus EP. Mayers JR, et al. Among authors: daniel ivad m. Cell. 2024 Jul 25;187(15):4095-4112.e21. doi: 10.1016/j.cell.2024.05.035. Epub 2024 Jun 16. Cell. 2024. PMID: 38885650 Free article.
Identification and targeting of microbial putrescine acetylation in bloodstream infections.
Mayers JR, Varon J, Zhou RR, Daniel-Ivad M, Beaulieu C, Bholse A, Glasser NR, Lichtenauer FM, Ng J, Vera MP, Huttenhower C, Perrella MA, Clish CB, Zhao SD, Baron RM, Balskus EP. Mayers JR, et al. Among authors: daniel ivad m. bioRxiv [Preprint]. 2023 Sep 21:2023.09.21.558834. doi: 10.1101/2023.09.21.558834. bioRxiv. 2023. PMID: 37790300 Free PMC article. Preprint.
A small molecule inhibitor prevents gut bacterial genotoxin production.
Volpe MR, Velilla JA, Daniel-Ivad M, Yao JJ, Stornetta A, Villalta PW, Huang HC, Bachovchin DA, Balbo S, Gaudet R, Balskus EP. Volpe MR, et al. Among authors: daniel ivad m. Nat Chem Biol. 2023 Feb;19(2):159-167. doi: 10.1038/s41589-022-01147-8. Epub 2022 Oct 17. Nat Chem Biol. 2023. PMID: 36253549 Free PMC article.
A small molecule produced by Lactobacillus species blocks Candida albicans filamentation by inhibiting a DYRK1-family kinase.
MacAlpine J, Daniel-Ivad M, Liu Z, Yano J, Revie NM, Todd RT, Stogios PJ, Sanchez H, O'Meara TR, Tompkins TA, Savchenko A, Selmecki A, Veri AO, Andes DR, Fidel PL Jr, Robbins N, Nodwell J, Whitesell L, Cowen LE. MacAlpine J, et al. Among authors: daniel ivad m. Nat Commun. 2021 Oct 22;12(1):6151. doi: 10.1038/s41467-021-26390-w. Nat Commun. 2021. PMID: 34686660 Free PMC article.
An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris.
Iyer KR, Camara K, Daniel-Ivad M, Trilles R, Pimentel-Elardo SM, Fossen JL, Marchillo K, Liu Z, Singh S, Muñoz JF, Kim SH, Porco JA Jr, Cuomo CA, Williams NS, Ibrahim AS, Edwards JE Jr, Andes DR, Nodwell JR, Brown LE, Whitesell L, Robbins N, Cowen LE. Iyer KR, et al. Among authors: daniel ivad m. Nat Commun. 2020 Dec 22;11(1):6429. doi: 10.1038/s41467-020-20183-3. Nat Commun. 2020. PMID: 33353950 Free PMC article.
Chemical entrapment and killing of insects by bacteria.
Ho LK, Daniel-Ivad M, Jeedigunta SP, Li J, Iliadi KG, Boulianne GL, Hurd TR, Smibert CA, Nodwell JR. Ho LK, et al. Among authors: daniel ivad m. Nat Commun. 2020 Sep 14;11(1):4608. doi: 10.1038/s41467-020-18462-0. Nat Commun. 2020. PMID: 32929085 Free PMC article.
A chemical defence against phage infection.
Kronheim S, Daniel-Ivad M, Duan Z, Hwang S, Wong AI, Mantel I, Nodwell JR, Maxwell KL. Kronheim S, et al. Among authors: daniel ivad m. Nature. 2018 Dec;564(7735):283-286. doi: 10.1038/s41586-018-0767-x. Epub 2018 Dec 5. Nature. 2018. PMID: 30518855
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