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Page 1
Chemo-Phosphoproteomic Profiling with ATR Inhibitors Berzosertib and Gartisertib Uncovers New Biomarkers and DNA Damage Response Regulators.
Jadav R, Weiland F, Noordermeer SM, Carroll T, Gao Y, Wang J, Zhou H, Lamoliatte F, Toth R, Macartney T, Brown F, Hastie CJ, Alabert C, van Attikum H, Zenke F, Masson JY, Rouse J. Jadav R, et al. Among authors: masson jy. Mol Cell Proteomics. 2024 Aug;23(8):100802. doi: 10.1016/j.mcpro.2024.100802. Epub 2024 Jun 15. Mol Cell Proteomics. 2024. PMID: 38880245 Free PMC article.
Cell Type Specific CAG Repeat Expansions and Toxicity of Mutant Huntingtin in Human Striatum and Cerebellum.
Mätlik K, Baffuto M, Kus L, Deshmukh AL, Davis DA, Paul MR, Carroll TS, Caron MC, Masson JY, Pearson CE, Heintz N. Mätlik K, et al. Among authors: masson jy. bioRxiv [Preprint]. 2023 Jun 8:2023.04.24.538082. doi: 10.1101/2023.04.24.538082. bioRxiv. 2023. Update in: Nat Genet. 2024 Mar;56(3):383-394. doi: 10.1038/s41588-024-01653-6. PMID: 37333326 Free PMC article. Updated. Preprint.
DNA polymerase θ protects leukemia cells from metabolically induced DNA damage.
Vekariya U, Toma M, Nieborowska-Skorska M, Le BV, Caron MC, Kukuyan AM, Sullivan-Reed K, Podszywalow-Bartnicka P, Chitrala KN, Atkins J, Drzewiecka M, Feng W, Chan J, Chatla S, Golovine K, Jelinek J, Sliwinski T, Ghosh J, Matlawska-Wasowska K, Chandramouly G, Nejati R, Wasik M, Sykes SM, Piwocka K, Hadzijusufovic E, Valent P, Pomerantz RT, Morton G, Childers W, Zhao H, Paietta EM, Levine RL, Tallman MS, Fernandez HF, Litzow MR, Gupta GP, Masson JY, Skorski T. Vekariya U, et al. Among authors: masson jy. Blood. 2023 May 11;141(19):2372-2389. doi: 10.1182/blood.2022018428. Blood. 2023. PMID: 36580665 Free PMC article.
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Gall-Duncan T, Luo J, Jurkovic CM, Fischer LA, Fujita K, Deshmukh AL, Harding RJ, Tran S, Mehkary M, Li V, Leib DE, Chen R, Tanaka H, Mason AG, Lévesque D, Khan M, Razzaghi M, Prasolava T, Lanni S, Sato N, Caron MC, Panigrahi GB, Wang P, Lau R, Castel AL, Masson JY, Tippett L, Turner C, Spies M, La Spada AR, Campos EI, Curtis MA, Boisvert FM, Faull RLM, Davidson BL, Nakamori M, Okazawa H, Wold MS, Pearson CE. Gall-Duncan T, et al. Among authors: masson jy. Cell. 2023 Oct 26;186(22):4898-4919.e25. doi: 10.1016/j.cell.2023.09.008. Epub 2023 Oct 11. Cell. 2023. PMID: 37827155 Free PMC article.
DNA polymerase theta-mediated DNA repair is a functional dependency and therapeutic vulnerability in DNMT3A deficient leukemia cells.
Le BV, Vekariya U, Toma MM, Nieborowska-Skorska M, Caron MC, Gozdecka M, Haydar Z, Walsh M, Ghosh J, Vaughan-Williams E, Podszywalow-Bartnicka P, Kukuyan AM, Ziolkowska S, Hadzijusufovic E, Chandramouly G, Piwocka K, Pomerantz R, Vassiliou GS, Huntly BJ, Valent P, Bellacosa A, Masson JY, Gupta GP, Challen GA, Skorski T. Le BV, et al. Among authors: masson jy. bioRxiv [Preprint]. 2024 Sep 19:2024.09.15.613155. doi: 10.1101/2024.09.15.613155. bioRxiv. 2024. PMID: 39411165 Free PMC article. Preprint.
SMARCAL1 ubiquitylation controls its association with RPA-coated ssDNA and promotes replication fork stability.
Yates M, Marois I, St-Hilaire E, Ronato DA, Djerir B, Brochu C, Morin T, Hammond-Martel I, Gezzar-Dandashi S, Casimir L, Drobetsky E, Cappadocia L, Masson JY, Wurtele H, Maréchal A. Yates M, et al. Among authors: masson jy. PLoS Biol. 2024 Mar 19;22(3):e3002552. doi: 10.1371/journal.pbio.3002552. eCollection 2024 Mar. PLoS Biol. 2024. PMID: 38502677 Free PMC article.
Human RAD52 stimulates the RAD51-mediated homology search.
Muhammad AA, Basto C, Peterlini T, Guirouilh-Barbat J, Thomas M, Veaute X, Busso D, Lopez B, Mazon G, Le Cam E, Masson JY, Dupaigne P. Muhammad AA, et al. Among authors: masson jy. Life Sci Alliance. 2023 Dec 11;7(3):e202201751. doi: 10.26508/lsa.202201751. Print 2024 Mar. Life Sci Alliance. 2023. PMID: 38081641 Free PMC article.
ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.
O'Sullivan J, Kothari C, Caron MC, Gagné JP, Jin Z, Nonfoux L, Beneyton A, Coulombe Y, Thomas M, Atalay N, Meng XW, Milano L, Jean D, Boisvert FM, Kaufmann SH, Hendzel MJ, Masson JY, Poirier GG. O'Sullivan J, et al. Among authors: masson jy. Nucleic Acids Res. 2023 Nov 10;51(20):11056-11079. doi: 10.1093/nar/gkad791. Nucleic Acids Res. 2023. PMID: 37823600 Free PMC article.
176 results