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Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors.
Rullo M, La Spada G, Miniero DV, Gottinger A, Catto M, Delre P, Mastromarino M, Latronico T, Marchese S, Mangiatordi GF, Binda C, Linusson A, Liuzzi GM, Pisani L. Rullo M, et al. Among authors: liuzzi gm. Eur J Med Chem. 2023 Jul 5;255:115352. doi: 10.1016/j.ejmech.2023.115352. Epub 2023 Apr 8. Eur J Med Chem. 2023. PMID: 37178666
Structure-based design of multitargeting ChEs-MAO B inhibitors based on phenyl ring bioisosteres: AChE/BChE selectivity switch and drug-like characterization.
La Spada G, Miniero DV, Rullo M, Cipolloni M, Delre P, Colliva C, Colella M, Leonetti F, Liuzzi GM, Mangiatordi GF, Giacchè N, Pisani L. La Spada G, et al. Among authors: liuzzi gm. Eur J Med Chem. 2024 Aug 5;274:116511. doi: 10.1016/j.ejmech.2024.116511. Epub 2024 May 19. Eur J Med Chem. 2024. PMID: 38820854 Free article.
Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity.
Al-Saad OM, Gabr M, Darwish SS, Rullo M, Pisani L, Miniero DV, Liuzzi GM, Kany AM, Hirsch AKH, Abadi AH, Engel M, Catto M, Abdel-Halim M. Al-Saad OM, et al. Among authors: liuzzi gm. Eur J Med Chem. 2024 Apr 5;269:116266. doi: 10.1016/j.ejmech.2024.116266. Epub 2024 Feb 28. Eur J Med Chem. 2024. PMID: 38490063 Free article.
Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease.
Tonelli M, Catto M, Sabaté R, Francesconi V, Laurini E, Pricl S, Pisani L, Miniero DV, Liuzzi GM, Gatta E, Relini A, Gavín R, Del Rio JA, Sparatore F, Carotti A. Tonelli M, et al. Among authors: liuzzi gm. Eur J Med Chem. 2023 Mar 15;250:115169. doi: 10.1016/j.ejmech.2023.115169. Epub 2023 Feb 2. Eur J Med Chem. 2023. PMID: 36753881 Free article.
Biomarkers of Neurological Damage: From Acute Stage to Post-Acute Sequelae of COVID-19.
Zingaropoli MA, Pasculli P, Barbato C, Petrella C, Fiore M, Dominelli F, Latronico T, Ciccone F, Antonacci M, Liuzzi GM, Talarico G, Bruno G, Galardo G, Pugliese F, Lichtner M, Mastroianni CM, Minni A, Ciardi MR. Zingaropoli MA, et al. Among authors: liuzzi gm. Cells. 2023 Sep 13;12(18):2270. doi: 10.3390/cells12182270. Cells. 2023. PMID: 37759493 Free PMC article.
Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) and Pulmonary Involvement in COVID-19 Pneumonia.
Zingaropoli MA, Latronico T, Pasculli P, Masci GM, Merz R, Ciccone F, Dominelli F, Del Borgo C, Lichtner M, Iafrate F, Galardo G, Pugliese F, Panebianco V, Ricci P, Catalano C, Ciardi MR, Liuzzi GM, Mastroianni CM. Zingaropoli MA, et al. Among authors: liuzzi gm. Biomolecules. 2023 Jun 26;13(7):1040. doi: 10.3390/biom13071040. Biomolecules. 2023. PMID: 37509076 Free PMC article.
82 results