Intersectin 2 controls actin cap formation and meiotic division in mouse oocytes through the Cdc42 pathway.
Zhang J, Ma R, Li L, Wang L, Hou X, Han L, Ge J, Li M, Wang Q.
Zhang J, et al. Among authors: ge j.
FASEB J. 2017 Oct;31(10):4277-4285. doi: 10.1096/fj.201700179R. Epub 2017 Jun 16.
FASEB J. 2017.
PMID: 28626024
In summary, our data support a model in which ITSN2 depletion induces the inactivation of Cdc42, which, in turn, influences the distribution and function of Arp2/3 and WASP, consequently disrupting oocyte polarity establishment and meiotic division.-Zhang, J., Ma, R., Li, …
In summary, our data support a model in which ITSN2 depletion induces the inactivation of Cdc42, which, in turn, influences the distribution …