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Genome-wide enhancer RNA profiling adds molecular links between genetic variation and human cancers.
Cai YM, Lu ZQ, Li B, Huang JY, Zhang M, Chen C, Fan LY, Ma QY, He CY, Chen SN, Jiang Y, Li YM, Ning CB, Zhang FW, Wang WZ, Liu YZ, Zhang H, Jin M, Wang XY, Han JX, Xiong Z, Cai M, Huang CQ, Yang XJ, Zhu X, Zhu Y, Miao XP, Zhang SK, Wei YC, Tian JB. Cai YM, et al. Among authors: huang jy, huang cq. Mil Med Res. 2024 Jun 11;11(1):36. doi: 10.1186/s40779-024-00539-2. Mil Med Res. 2024. PMID: 38863031 Free PMC article.
Aberrant RNA Splicing Is a Primary Link between Genetic Variation and Pancreatic Cancer Risk.
Tian J, Chen C, Rao M, Zhang M, Lu Z, Cai Y, Ying P, Li B, Wang H, Wang L, Li Y, Huang J, Fan L, Cai X, Ning C, Li Y, Zhang F, Wang W, Jiang Y, Liu Y, Wang M, Li H, Huang C, Yang Z, Chang J, Zhu Y, Yang X, Miao X. Tian J, et al. Cancer Res. 2022 Jun 6;82(11):2084-2096. doi: 10.1158/0008-5472.CAN-21-4367. Cancer Res. 2022. PMID: 35363263
Pan-Cancer Analysis of Microbiome Quantitative Trait Loci.
Chen C, Cai Y, Liu Y, Chen S, Li Y, Zhang F, Zhang M, Lu Z, Ying P, Huang J, Fan L, Cai X, Ning C, Wang W, Jiang Y, Zhang H, Yang S, Wang Z, Wang X, Zhang S, Huang C, Xu B, Fu Z, Song Q, Jin M, Chen K, Chen H, Dai M, Miao X, Yang X, Zhu Y, Tian J. Chen C, et al. Cancer Res. 2022 Oct 4;82(19):3449-3456. doi: 10.1158/0008-5472.CAN-22-1854. Cancer Res. 2022. PMID: 35972351
HSPA12A was identified as a key driver in colorectal cancer GWAS loci 10q26.12 and modulated by an enhancer-promoter interaction.
Lu Z, Fan L, Zhang F, Huang C, Cai Y, Chen C, Li G, Zhang M, Huang J, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Ye T, Liu J, Yang X, Xu B, Zhu Y, Zhong R, Li H, Tian J, Li B, Miao X. Lu Z, et al. Arch Toxicol. 2023 Jul;97(7):2015-2028. doi: 10.1007/s00204-023-03494-4. Epub 2023 May 28. Arch Toxicol. 2023. PMID: 37245169
Genetic Control of Alternative Splicing and its Distinct Role in Colorectal Cancer Mechanisms.
Zhang M, Chen C, Lu Z, Cai Y, Li Y, Zhang F, Liu Y, Chen S, Zhang H, Yang S, Gen H, Jiang Y, Ning C, Huang J, Wang W, Fan L, Zhang Y, Jin M, Han J, Xiong Z, Cai M, Liu J, Huang C, Yang X, Xu B, Li H, Li B, Zhu X, Wei Y, Zhu Y, Tian J, Miao X. Zhang M, et al. Gastroenterology. 2023 Nov;165(5):1151-1167. doi: 10.1053/j.gastro.2023.07.019. Epub 2023 Aug 3. Gastroenterology. 2023. PMID: 37541527
Genetic Variants That Impact Alternative Polyadenylation in Cancer Represent Candidate Causal Risk Loci.
Li B, Cai Y, Chen C, Li G, Zhang M, Lu Z, Zhang F, Huang J, Fan L, Ning C, Li Y, Wang W, Geng H, Liu Y, Chen S, Li H, Yang S, Zhang H, Tian W, Zhu Z, Xu B, Li H, Li H, Jin M, Wang X, Zhang S, Liu J, Huang C, Yang X, Wei Y, Zhu Y, Tian J, Miao X. Li B, et al. Cancer Res. 2023 Nov 1;83(21):3650-3666. doi: 10.1158/0008-5472.CAN-23-0251. Cancer Res. 2023. PMID: 37669142
An atlas of genetic effects on cellular composition of the tumor microenvironment.
Cai Y, Lu Z, Chen C, Zhu Y, Chen Z, Wu Z, Peng J, Zhu X, Liu Z, Li B, Zhang M, Huang J, Li Y, Liu Y, Ma Q, He C, Chen S, Tian W, Fan L, Ning C, Geng H, Xu B, Li H, Zhu X, Fang J, Wang X, Zhang S, Jin M, Huang C, Yang X, Tian J, Miao X. Cai Y, et al. Nat Immunol. 2024 Oct;25(10):1959-1975. doi: 10.1038/s41590-024-01945-3. Epub 2024 Sep 2. Nat Immunol. 2024. PMID: 39223350
1,596 results