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Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA).
Overbey EG, Ryon K, Kim J, Tierney BT, Klotz R, Ortiz V, Mullane S, Schmidt JC, MacKay M, Damle N, Najjar D, Matei I, Patras L, Garcia Medina JS, Kleinman AS, Wain Hirschberg J, Proszynski J, Narayanan SA, Schmidt CM, Afshin EE, Innes L, Saldarriaga MM, Schmidt MA, Granstein RD, Shirah B, Yu M, Lyden D, Mateus J, Mason CE. Overbey EG, et al. Among authors: schmidt jc. Nat Commun. 2024 Jun 11;15(1):4964. doi: 10.1038/s41467-024-48806-z. Nat Commun. 2024. PMID: 38862509 Free PMC article.
Metabolomics as a Truly Translational Tool for Precision Medicine.
Schmidt JC, Dougherty BV, Beger RD, Jones DP, Schmidt MA, Mattes WB. Schmidt JC, et al. Among authors: schmidt ma. Int J Toxicol. 2021 Oct;40(5):413-426. doi: 10.1177/10915818211039436. Int J Toxicol. 2021. PMID: 34514887 Free PMC article. Review.
Collection of Biospecimens from the Inspiration4 Mission Establishes the Standards for the Space Omics and Medical Atlas (SOMA).
Overbey EG, Ryon K, Kim J, Tierney B, Klotz R, Ortiz V, Mullane S, Schmidt JC, MacKay M, Damle N, Najjar D, Matei I, Patras L, Medina JSG, Kleinman A, Hirschberg JW, Proszynski J, Narayanan SA, Schmidt CM, Afshin EE, Innes L, Saldarriaga MM, Schmidt MA, Granstein RD, Shirah B, Yu M, Lyden D, Mateus J, Mason CE. Overbey EG, et al. Among authors: schmidt ma, schmidt jc, schmidt cm. bioRxiv [Preprint]. 2023 May 2:2023.05.02.539108. doi: 10.1101/2023.05.02.539108. bioRxiv. 2023. Update in: Nat Commun. 2024 Jun 11;15(1):4964. doi: 10.1038/s41467-024-48806-z. PMID: 37205403 Free PMC article. Updated. Preprint.
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight.
Garcia-Medina JS, Sienkiewicz K, Narayanan SA, Overbey EG, Grigorev K, Ryon KA, Burke M, Proszynski J, Tierney B, Schmidt CM, Mencia-Trinchant N, Klotz R, Ortiz V, Foox J, Chin C, Najjar D, Matei I, Chan I, Cruchaga C, Kleinman A, Kim J, Lucaci A, Loy C, Mzava O, De Vlaminck I, Singaraju A, Taylor LE, Schmidt JC, Schmidt MA, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Altomare A, Kruglyak S, Levy S, Yu M, Hassane DC, Bailey SM, Bolton K, Mateus J, Mason CE. Garcia-Medina JS, et al. Among authors: schmidt ma, schmidt jc, schmidt cm. Precis Clin Med. 2024 Apr 8;7(1):pbae007. doi: 10.1093/pcmedi/pbae007. eCollection 2024 Mar. Precis Clin Med. 2024. PMID: 38634106 Free PMC article.
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank.
Overbey EG, Kim J, Tierney BT, Park J, Houerbi N, Lucaci AG, Garcia Medina S, Damle N, Najjar D, Grigorev K, Afshin EE, Ryon KA, Sienkiewicz K, Patras L, Klotz R, Ortiz V, MacKay M, Schweickart A, Chin CR, Sierra MA, Valenzuela MF, Dantas E, Nelson TM, Cekanaviciute E, Deards G, Foox J, Narayanan SA, Schmidt CM, Schmidt MA, Schmidt JC, Mullane S, Tigchelaar SS, Levitte S, Westover C, Bhattacharya C, Lucotti S, Wain Hirschberg J, Proszynski J, Burke M, Kleinman AS, Butler DJ, Loy C, Mzava O, Lenz J, Paul D, Mozsary C, Sanders LM, Taylor LE, Patel CO, Khan SA, Suhail Mohamad M, Byhaqui SGA, Aslam B, Gajadhar AS, Williamson L, Tandel P, Yang Q, Chu J, Benz RW, Siddiqui A, Hornburg D, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Scott RT, Gilbert RR, Lai Polo SH, Altomare A, Kruglyak S, Levy S, Ariyapala I, Beer J, Zhang B, Hudson BM, Rininger A, Church SE, Beheshti A, Church GM, Smith SM, Crucian BE, Zwart SR, Matei I, Lyden DC, Garrett-Bakelman F, Krumsiek J, Chen Q, Miller D, Shuga J, Williams S, Nemec C, Trudel G, Pelchat M, Laneuville O, De Vlaminck I, Gross S, Bolton KL, Bailey SM, Granstein R, Furman D, Melnick AM, Costes SV, Shirah B, Yu M, Menon AS, Mateus J, Mey… See abstract for full author list ➔ Overbey EG, et al. Among authors: schmidt jc. Nature. 2024 Aug;632(8027):1145-1154. doi: 10.1038/s41586-024-07639-y. Epub 2024 Jun 11. Nature. 2024. PMID: 38862028 Free PMC article.
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Kim J, Tierney BT, Overbey EG, Dantas E, Fuentealba M, Park J, Narayanan SA, Wu F, Najjar D, Chin CR, Meydan C, Loy C, Mathyk B, Klotz R, Ortiz V, Nguyen K, Ryon KA, Damle N, Houerbi N, Patras LI, Schanzer N, Hutchinson GA, Foox J, Bhattacharya C, Mackay M, Afshin EE, Hirschberg JW, Kleinman AS, Schmidt JC, Schmidt CM, Schmidt MA, Beheshti A, Matei I, Lyden D, Mullane S, Asadi A, Lenz JS, Mzava O, Yu M, Ganesan S, De Vlaminck I, Melnick AM, Barisic D, Winer DA, Zwart SR, Crucian BE, Smith SM, Mateus J, Furman D, Mason CE. Kim J, et al. Among authors: schmidt jc. Nat Commun. 2024 Jun 11;15(1):4954. doi: 10.1038/s41467-024-49211-2. Nat Commun. 2024. PMID: 38862516 Free PMC article.
A Multiomics, Molecular Atlas of Breast Cancer Survivors.
Bauer BA, Schmidt CM, Ruddy KJ, Olson JE, Meydan C, Schmidt JC, Smith SY, Couch FJ, Earls JC, Price ND, Dudley JT, Mason CE, Zhang B, Phipps SM, Schmidt MA. Bauer BA, et al. Among authors: schmidt jc. Metabolites. 2024 Jul 20;14(7):396. doi: 10.3390/metabo14070396. Metabolites. 2024. PMID: 39057719 Free PMC article.
DNA-PK: A synopsis beyond synapsis.
Goff NJ, Mikhova M, Schmidt JC, Meek K. Goff NJ, et al. Among authors: schmidt jc. DNA Repair (Amst). 2024 Sep;141:103716. doi: 10.1016/j.dnarep.2024.103716. Epub 2024 Jul 8. DNA Repair (Amst). 2024. PMID: 38996771 Review.
154 results